Mir-337

MirGeneDB ID

Mmu-Mir-337

Family name

MIR-337 (all species)

Species

House mouse (Mus musculus)

MiRBase ID

mmu-mir-337

Paralogues

Mmu-Mir-337-as

Orthologues

Cja-Mir-337 Cpo-Mir-337-v1 Dno-Mir-337-v1 Eca-Mir-337 Eca-Mir-337-as Hsa-Mir-337-as Hsa-Mir-337-v1 Laf-Mir-337 Mml-Mir-337-as Mml-Mir-337-v1 Mmr-Mir-337-v1 Ocu-Mir-337-as Ocu-Mir-337-v1 Pab-Mir-337 Rno-Mir-337 Rno-Mir-337-as

Node of Origin (locus)

Eutheria

Node of Origin (family)

Eutheria

Genome context
(mm10)

chr12: 109585818-109585871 [+] UCSC Ensembl

Clustered miRNAs
(< 50kb from Mir-337)

Mir-770 chr12: 109563710-109563765 [+] UCSC Ensembl
Mir-673 chr12: 109572004-109572066 [+] UCSC Ensembl
Mir-493 chr12: 109580243-109580305 [+] UCSC Ensembl
Mir-337-as chr12: 109585813-109585873 [-] UCSC Ensembl
Mir-337 chr12: 109585818-109585871 [+] UCSC Ensembl
Mir-540 chr12: 109586085-109586143 [+] UCSC Ensembl
Mir-431 chr12: 109590459-109590522 [+] UCSC Ensembl
Mir-433 chr12: 109591729-109591802 [+] UCSC Ensembl
Mir-127 chr12: 109592854-109592909 [+] UCSC Ensembl
Mir-434 chr12: 109594527-109594586 [+] UCSC Ensembl
Mir-136-v2 chr12: 109595331-109595386 [+] UCSC Ensembl
Mir-136-v1 chr12: 109595331-109595386 [+] UCSC Ensembl
Mir-370 chr12: 109618270-109618326 [+] UCSC Ensembl

Seed

GGCGUCA

Precursor
(pre-Mir +30nt flank)

CCAGUGUAGUGAGAAGUUGGGGGGUGGGAACGGCGUCAUGCAGGAGUUGAUUGCACAGCCAUUCAGCUCCUAUAUGAUGCCUUUCUUCACCCCCUUCAACCGCGUGAGGCCUCC

Get precursor sequence

Structure

        10         20         30        40        50      
CCAGUGUAGUGAGAAGUU-        -|   C         C         UUGCA 
                   GGGGGGUG GGAA GGCGUCAUG AGGAGUUGA     C
                   UCCCCCAC UCUU CCGUAGUAU UCCUCGACU     A
CCUCCGGAGUGCGCCAACU        U^   U         A         UACCG 
  110       100        90        80        70        60

Deep sequencing

Go to detailed chart

Comment

The Drosha cut in murids is shifted +3 and the gene is arm switched relative to the other eutherians.

3' NTU

Motifs

CNNC at 3p(+17)

Tissue expression

Br	Br	Ce	Ce	Em	Em	He	Ki	Li	Lu	Ov	Pa	Sk	Sp	Te

Mature sequence

Mmu-Mir-337_5p

mirBase accession

MIMAT0004644

Sequence

0- CGGCGUCAUGCAGGAGUUGAUU -22

Get sequence

Proposed targets

microrna.org: MIMAT0004644
TargetScanVert: mmu-miR-337-5p
miRDB: MIMAT0004644

Star sequence

Mmu-Mir-337_3p*

mirBase accession

MIMAT0000578

Sequence

32- UCAGCUCCUAUAUGAUGCCUUU -54

Get sequence

Proposed targets

microrna.org: MIMAT0000578
TargetScanVert: mmu-miR-337-3p
miRDB: MIMAT0000578