Mir-337

MirGeneDB ID

Rno-Mir-337

Family name

MIR-337 (all species)

Species

Norway rat (Rattus norvegicus)

MiRBase ID

rno-mir-337

Paralogues

Rno-Mir-337-as

Orthologues

Cja-Mir-337 Cpo-Mir-337-v1 Dno-Mir-337-v1 Eca-Mir-337 Eca-Mir-337-as Hsa-Mir-337-as Hsa-Mir-337-v1 Laf-Mir-337 Mml-Mir-337-as Mml-Mir-337-v1 Mmr-Mir-337-v1 Mmu-Mir-337 Mmu-Mir-337-as Ocu-Mir-337-as Ocu-Mir-337-v1 Pab-Mir-337

Node of Origin (locus)

Eutheria

Node of Origin (family)

Eutheria

Genome context
(rn6)

chr6: 133705948-133706001 [+] UCSC Ensembl

Clustered miRNAs
(< 50kb from Mir-337)

Mir-770 chr6: 133682975-133683030 [+] UCSC Ensembl
Mir-673 chr6: 133691391-133691453 [+] UCSC Ensembl
Mir-493 chr6: 133699522-133699583 [+] UCSC Ensembl
Mir-337-as chr6: 133705943-133706003 [-] UCSC Ensembl
Mir-337 chr6: 133705948-133706001 [+] UCSC Ensembl
Mir-540 chr6: 133706216-133706274 [+] UCSC Ensembl
Mir-431 chr6: 133711444-133711507 [+] UCSC Ensembl
Mir-433 chr6: 133712345-133712418 [+] UCSC Ensembl
Mir-127 chr6: 133713452-133713507 [+] UCSC Ensembl
Mir-136-v2 chr6: 133716775-133716830 [+] UCSC Ensembl
Mir-136-v1 chr6: 133716775-133716830 [+] UCSC Ensembl
Mir-370 chr6: 133739928-133739984 [+] UCSC Ensembl

Seed

GGCGUCA

Precursor
(pre-Mir +30nt flank)

CCAGUGUAGUGAGAAGUUGGGGGGUGGGAACGGCGUCAUGCAGGAGUUGAUUGCACAGCCAUUCAGCUCCUAUAUGAUGCCUUUCUUCACCCCCUUCAACCGCGUGUGGCGUCC

Get precursor sequence

Structure

        10         20         30        40        50      
CCAGUGUAGUGAGAAGUU-        -|   C         C         UUGCA 
                   GGGGGGUG GGAA GGCGUCAUG AGGAGUUGA     C
                   UCCCCCAC UCUU CCGUAGUAU UCCUCGACU     A
CCUGCGGUGUGCGCCAACU        U^   U         A         UACCG 
  110       100        90        80        70        60

Deep sequencing

Go to detailed chart

Comment

The Drosha cut in murids is shifted +3 and the gene is arm switched relative to the other eutherians.

3' NTU

Motifs

CNNC at 3p(+17)

Tissue expression

Dr	Dr	Ad	Bi	Bi	Bi	Bi	Br	Br	Br	Br	Ce	Ce	Ce	Ce	Co	Co	Co	Co	Du	Du	Du	Du	Fa	He	He	He	Hi	Hi	Il	Il	Je	Je	Ki	Ki	Ki	Ki	Ki	La	Li	Li	Li	Li	Li	Li	Lu	Me	Me	Mu	Ov	Pa	Pa	Pa	Sk	Sm	So	So	So	So	Sp	St	St	St	St	Te	Te	Th	Ut	Wh

Mature sequence

Rno-Mir-337_5p

mirBase accession

MIMAT0017035

Sequence

0- CGGCGUCAUGCAGGAGUUGAUU -22

Get sequence

Proposed targets

TargetScanVert: rno-miR-337-5p
miRDB: MIMAT0017035

Star sequence

Rno-Mir-337_3p*

mirBase accession

MIMAT0000577

Sequence

32- UCAGCUCCUAUAUGAUGCCUUU -54

Get sequence

Proposed targets

microrna.org: MIMAT0000577
TargetScanVert: rno-miR-337-3p
miRDB: MIMAT0000577