Mir-193-P2a

MirGeneDB ID

Hsa-Mir-193-P2a

Family name

MIR-193 (all species)

Species

Human (Homo sapiens)

MiRBase ID

hsa-mir-365a

Paralogues

Hsa-Mir-193-P1a Hsa-Mir-193-P1b Hsa-Mir-193-P2b

Orthologues

Ami-Mir-193-P2a Bge-Mir-193-P2 Bta-Mir-193-P2a Cbr-Mir-193-P2-v1 Cel-Mir-193-P2-v1 Cfa-Mir-193-P2a Cja-Mir-193-P2a Cli-Mir-193-P2a Cmi-Mir-193-P2a Cpi-Mir-193-P2a Cpo-Mir-193-P2a Cte-Mir-193-P2 Dgr-Mir-193-P2 Dlo-Mir-193-P2 Dno-Mir-193-P2a Dre-Mir-193-P2a Ebu-Mir-193-P2 Eca-Mir-193-P2a Ete-Mir-193-P2a Gga-Mir-193-P2a Hme-Mir-193-P2 Hru-Mir-193-P2 Laf-Mir-193-P2a Lch-Mir-193-P2a Lgi-Mir-193-P2 Llo-Mir-193-P2-v1 Loc-Mir-193-P2a Mdo-Mir-193-P2a Mgi-Mir-193-P2 Mml-Mir-193-P2a Mmr-Mir-193-P2a Mmu-Mir-193-P2a Mun-Mir-193-P2a Neu-Mir-193-P2a Oan-Mir-193-P2a Ocu-Mir-193-P2a Pab-Mir-193-P2a Pau-Mir-193-P2 Pbv-Mir-193-P2a Pdu-Mir-193-P2 Pfl-Mir-193-P2 Pma-Mir-193-P2 Pmi-Mir-193-P2 Pve-Mir-193-P2 Rno-Mir-193-P2a Rph-Mir-193-P2 Sha-Mir-193-P2a Sko-Mir-193-P2 Snu-Mir-193-P2 Spt-Mir-193-P2a Spu-Mir-193-P2 Sro-Mir-193-P2 Sto-Mir-193-P2a Tca-Mir-193-P2 Tgu-Mir-193-P2a Xbo-Mir-193-P2 Xla-Mir-193-P2a3 Xla-Mir-193-P2a4 Xtr-Mir-193-P2a

Node of Origin (locus)

Vertebrata

Node of Origin (family)

Bilateria

Genome context
(hg38)

chr16: 14309300-14309360 [+] UCSC Ensembl

Clustered miRNAs
(< 50kb from Mir-193-P2a)

Mir-193-P1a chr16: 14303980-14304038 [+] UCSC Ensembl
Mir-193-P2a chr16: 14309300-14309360 [+] UCSC Ensembl

Seed

AAUGCCC

Precursor
(pre-Mir +30nt flank)

GCCAGCUGGUUCGUUACCGCAGGGAAAAUGAGGGACUUUUGGGGGCAGAUGUGUUUCCAUUCCACUAUCAUAAUGCCCCUAAAAAUCCUUAUUGCUCUUGCAGUAUUCCUCGGGGGUCCCU

Get precursor sequence

Structure

        10          20        30        40        50        60 
GCCAGCUGGUUCGUUACC--|     AA        AC           GA    UUUCCAU 
                    GCAGGG  AAUGAGGG  UUUUGGGGGCA  UGUG       \
                    CGUUCU  UUAUUCCU  AAAAUCCCCGU  AUAC       U
UCCCUGGGGGCUCCUUAUGA^     CG        A-           A-    UAUCACC 
 .       110       100        90         80         70

Deep sequencing

Go to detailed chart

Comment

Although there is a templated T at the 3' end of the 3p arm, the post-transcriptional addition of a terminal 3' U is supported by the CAGE data from de Rie et al. (2017). All other osteichthyians are treated accordingly. There is also a second Drosha cut -1 on both arms.

3' NTU

Yes

Motifs

CNNC at 3p(+17)

Tissue expression

Dc	Dc	Dr	Dr	Xp	Xp	Bl	Br	Br	Ce	Ce	Co	Fo	He	Ki	Le	Li	Li	Lu	Pa	Pl	Pl	Sk	Sk	Sk	Sm	Sp	Sp	St	Te	Th	Ut

Star sequence

Hsa-Mir-193-P2a_5p*

mirBase accession

MIMAT0009199

Sequence

0- AGGGACUUUUGGGGGCAGAUGUG -23

Get sequence

Proposed targets

microrna.org: MIMAT0009199
TargetScanVert: hsa-miR-365a-5p
TargetMiner: hsa-miR-365a-5p
miRDB: MIMAT0009199

Mature sequence

Hsa-Mir-193-P2a_3p

mirBase accession

MIMAT0000710

Sequence

40- UAAUGCCCCUAAAAAUCCUUA -61

Get sequence

Proposed targets

microrna.org: MIMAT0000710
TargetScanVert: hsa-miR-365a-3p
TargetMiner: hsa-miR-365a-3p
miRDB: MIMAT0000710