Mir-1-P2

MirGeneDB ID

Hsa-Mir-1-P2

Family name

MIR-1 (all species)

Species

Human (Homo sapiens)

MiRBase ID

hsa-mir-206

Paralogues

Hsa-Mir-1-P1 Hsa-Mir-1-P3

Orthologues

Aae-Mir-1 Aca-Mir-1-P2 Aga-Mir-1 Agr-Mir-1 Ami-Mir-1-P2 Asu-Mir-1 Bfl-Mir-1 Bge-Mir-1 Bla-Mir-1 Bta-Mir-1-P2 Cbr-Mir-1 Cel-Mir-1 Cfa-Mir-1-P2 Cin-Mir-1 Cja-Mir-1-P2 Cli-Mir-1-P2 Cpi-Mir-1-P2 Cpo-Mir-1-P2 Cte-Mir-1 Dan-Mir-1 Dgr-Mir-1 Dlo-Mir-1 Dma-Mir-1 Dme-Mir-1 Dmo-Mir-1 Dno-Mir-1-P2 Dpu-Mir-1 Dre-Mir-1-P2a Dre-Mir-1-P2b Dsi-Mir-1 Dya-Mir-1 Eba-Mir-1 Eca-Mir-1-P2 Egr-Mir-1 Esc-Mir-1 Ete-Mir-1-P2 Gga-Mir-1-P2 Gja-Mir-1-P2e Gja-Mir-1-P2f Gmo-Mir-1-P2a Gpa-Mir-1 Gsa-Mir-1 Gsp-Mir-1 Hme-Mir-1 Hmi-Mir-1 Hru-Mir-1 Isc-Mir-1 Laf-Mir-1-P2 Lan-Mir-1 Lch-Mir-1-P2 Lgi-Mir-1 Lhy-Mir-1 Llo-Mir-1 Loc-Mir-1-P2 Mal-Mir-1-P2a Mdo-Mir-1-P2 Mgi-Mir-1 Mml-Mir-1-P2 Mmr-Mir-1-P2 Mmu-Mir-1-P2 Mom-Mir-1 Mun-Mir-1-P2 Oan-Mir-1-P2 Obi-Mir-1 Ocu-Mir-1-P2 Ofu-Mir-1 Ovu-Mir-1 Pab-Mir-1-P2 Pau-Mir-1 Pbv-Mir-1-P2 Pca-Mir-1 Pcr-Mir-1 Pdu-Mir-1 Pfl-Mir-1 Ple-Mir-1 Pma-Mir-1-o2 Pmi-Mir-1 Rno-Mir-1-P2 Rph-Mir-1 Sha-Mir-1-P2 Sko-Mir-1 Sma-Mir-1 Sne-Mir-1 Snu-Mir-1 Spt-Mir-1-P2 Spu-Mir-1 Sro-Mir-1 Tca-Mir-1 Tgu-Mir-1-P2 Tni-Mir-1-P2a Tur-Mir-1 War-Mir-1 Xbo-Mir-1 Xla-Mir-1-P2c Xla-Mir-1-P2d Xtr-Mir-1-P2

Node of Origin (locus)

Gnathostomata

Node of Origin (family)

Bilateria

Genome context
(hg38)

chr6: 52144363-52144422 [+] UCSC Ensembl

Clustered miRNAs
(< 50kb from Mir-1-P2)

Mir-1-P2 chr6: 52144363-52144422 [+] UCSC Ensembl
Mir-133-P2-v1 chr6: 52148951-52149009 [+] UCSC Ensembl
Mir-133-P2-v2 chr6: 52148951-52149009 [+] UCSC Ensembl

Seed

GGAAUGU

Precursor
(pre-Mir +30nt flank)

UGCUUCUGGAUGACACUGCUUCCCGAGGCCACAUGCUUCUUUAUAUCCCCAUAUGGAUUACUUUGCUAUGGAAUGUAAGGAAGUGUGUGGUUUCGGCAAGUGCCUCCUCGCUGGCCCCAG

Get precursor sequence

Structure

        10          20        30        40        50          
UGCUUCUGGAUGACACU--|   C                        CC     UGGAUU 
                   GCUU CCGAGGCCACAUGCUUCUUUAUAU  CCAUA      \
                   UGAA GGCUUUGGUGUGUGAAGGAAUGUA  GGUAU      A
GACCCCGGUCGCUCCUCCG^   C                        A-     CGUUUC 
.       110       100        90        80         70

Deep sequencing

Go to detailed chart

3' NTU

Motifs

UG at 5p(-14), CNNC at 3p(+17)

Tissue expression

Dc	Dc	Dr	Dr	Xp	Xp	Bl	Br	Br	Ce	Ce	Co	Fo	He	Ki	Le	Li	Li	Lu	Pa	Pl	Pl	Sk	Sk	Sk	Sm	Sp	Sp	St	Te	Th	Ut

Star sequence

Hsa-Mir-1-P2_5p*

mirBase accession

None

Sequence

0- ACAUGCUUCUUUAUAUCCCCAUA -23

Get sequence

Mature sequence

Hsa-Mir-1-P2_3p

mirBase accession

MIMAT0000462

Sequence

38- UGGAAUGUAAGGAAGUGUGUGG -60

Get sequence

Proposed targets

microrna.org: MIMAT0000462
TargetScanVert: hsa-miR-206
TargetMiner: hsa-miR-206
miRDB: MIMAT0000462