Let-7-P2c1

MirGeneDB ID

Eca-Let-7-P2c1

Family name

LET-7 (all species)

Species

Horse (Equus caballus)

MiRBase ID

eca-let-7d

Paralogues

Eca-Let-7-P1b Eca-Let-7-P1c Eca-Let-7-P1d Eca-Let-7-P2a1 Eca-Let-7-P2a2 Eca-Let-7-P2a3 Eca-Let-7-P2b1 Eca-Let-7-P2b2 Eca-Let-7-P2b3 Eca-Let-7-P2c2 Eca-Let-7-P2c3

Orthologues

Aae-Let-7 Aca-Let-7-P2c1 Aga-Let-7 Agr-Let-7 Ami-Let-7-P2c1 Bge-Let-7 Bko-Let-7 Bpl-Let-7 Bta-Let-7-P2c1 Cfa-Let-7-P2c1 Cja-Let-7-P2c1 Cli-Let-7-P2c1 Cmi-Let-7-P2c1 Cpi-Let-7-P2c1 Cpo-Let-7-P2c1 Cte-Let-7 Dan-Let-7 Dlo-Let-7 Dma-Let-7 Dme-Let-7 Dmo-Let-7 Dno-Let-7-P2c1 Dpu-Let-7 Dsi-Let-7 Dya-Let-7 Eba-Let-7 Egr-Let-7 Esc-Let-7 Ete-Let-7-P2c1 Gga-Let-7-P2c1 Gja-Let-7-P2c1 Gpa-Let-7 Gsa-Let-7 Gsp-Let-7 Hme-Let-7 Hmi-Let-7 Hru-Let-7 Hsa-Let-7-P2c1 Isc-Let-7 Laf-Let-7-P2c1 Lan-Let-7 Lch-Let-7-P2c1 Lgi-Let-7 Lhy-Let-7 Llo-Let-7 Loc-Let-7-P2c1 Mdo-Let-7-P2c1 Mgi-Let-7 Mml-Let-7-P2c1 Mmr-Let-7-P2c1 Mmu-Let-7-P2c1 Mom-Let-7 Mun-Let-7-P2c1 Neu-Let-7-P2c1 Npo-Let-7 Oan-Let-7-P2c1 Obi-Let-7 Ocu-Let-7-P2c1 Ofu-Let-7 Ovu-Let-7 Pab-Let-7-P2c1 Pau-Let-7 Pbv-Let-7-P2c1 Pca-Let-7 Pcr-Let-7 Pdu-Let-7 Pfl-Let-7 Ple-Let-7 Pmi-Let-7 Pve-Let-7 Rno-Let-7-P2c1 Rph-Let-7 Sha-Let-7-P2c1 Sko-Let-7 Sma-Let-7 Sne-Let-7 Snu-Let-7 Spt-Let-7-P2c1 Spu-Let-7 Sro-Let-7 Sto-Let-7-P2c1 Tca-Let-7 Tgu-Let-7-P2c1 Tur-Let-7 War-Let-7 Xbo-Let-7

Node of Origin (locus)

Gnathostomata

Node of Origin (family)

Bilateria

Genome context
(GCA_002863925.1_EquCab3.0)

CM009170.1: 53957806-53957880 [-] UCSC Ensembl

Clustered miRNAs
(< 50kb from Let-7-P2c1)

Let-7-P2c1 CM009170.1: 53957806-53957880 [-] UCSC Ensembl
Let-7-P2b1 CM009170.1: 53959745-53959821 [-] UCSC Ensembl
Let-7-P2a1 CM009170.1: 53960138-53960209 [-] UCSC Ensembl

Seed

GAGGUAG

Precursor
(pre-Mir +30nt flank)

ACCGGCAAGAAAAAAAAUGGGUUCCUAGGAAGAGGUAGUAGGUUGCAUAGUUUUAGGGCAGGGAUUUUGCCCACAAGGAGAUAACUAUACGACCUGCUGCCUUUCUUAGGGCCUGAUUAUUCCACGGUCACCUGU

Get precursor sequence

Structure

        10           20        30        40        50        60       
ACCGGCAAGAAAAAAAAU---|   U       A              C      UUAGGGCAGGGAUU 
                     GGGU CCUAGGA GAGGUAGUAGGUUG AUAGUU              U
                     UCCG GGAUUCU UUCCGUCGUCCAGC UAUCAA              U
UGUCCACUGGCACCUUAUUAG^   -       -              A      UAGAGGAACACCCG 
   130       120        110        100        90        80        70

Deep sequencing

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Comment

The 3'DcRNA read in cow is consistent with this gene being classified as a Group 2 miRNA.

3' NTU

Yes

Motifs

CNNC at 3p(+17)

Tissue expression

Ps	Bo	Ca	Em	En	En	En	En	En	En	En	Gl	He	He	Ho	Im	Ki	Li	Lo	Lu	Ma	Ma	Mi	Pl	Sp	Te	Tr	Ut	Ut	Yo

Mature sequence

Eca-Let-7-P2c1_5p

mirBase accession

MIMAT0013110

Sequence

0- AGAGGUAGUAGGUUGCAUAGUU -22

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Star sequence

Eca-Let-7-P2c1_3p*

mirBase accession

None

Sequence

54- CUAUACGACCUGCUGCCUUUC -75

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