Mir-8-P1a

MirGeneDB ID

Sto-Mir-8-P1a

Family name

MIR-8 (all species)

Species

Cloudy Catshark (Scyliorhinus torazame)

MiRBase ID

Paralogues

Sto-Mir-8-P2a Sto-Mir-8-P3a

Orthologues

Aae-Mir-8 Aca-Mir-8-P1a Aga-Mir-8 Agr-Mir-8 Ami-Mir-8-P1a Asu-Mir-8 Bfl-Mir-8-P1-v1 Bge-Mir-8 Bko-Mir-8 Bla-Mir-8-P1 Bpl-Mir-8 Bta-Mir-8-P1a Cbr-Mir-8 Cel-Mir-8 Cfa-Mir-8-P1a Cin-Mir-8-P1 Cja-Mir-8-P1a Cli-Mir-8-P1a Cmi-Mir-8-P1a Cpi-Mir-8-P1a Cpo-Mir-8-P1a Csc-Mir-8 Cte-Mir-8 Dan-Mir-8 Dgr-Mir-8 Dlo-Mir-8 Dma-Mir-8 Dme-Mir-8 Dmo-Mir-8 Dno-Mir-8-P1a Dpu-Mir-8 Dre-Mir-8-P1a Dsi-Mir-8 Dya-Mir-8 Eba-Mir-8 Eca-Mir-8-P1a Eca-Mir-8-P1a-as Egr-Mir-8 Esc-Mir-8 Ete-Mir-8-P1a Gga-Mir-8-P1a Gja-Mir-8-P1a Gmo-Mir-8-P1a Gpa-Mir-8 Gsa-Mir-8 Hme-Mir-8 Hru-Mir-8 Hsa-Mir-8-P1a Isc-Mir-8 Laf-Mir-8-P1a Lan-Mir-8 Lch-Mir-8-P1a Lgi-Mir-8 Lhy-Mir-8 Llo-Mir-8 Loc-Mir-8-P1a Mal-Mir-8-P1a Mdo-Mir-8-P1a Mgi-Mir-8 Mml-Mir-8-P1a Mmr-Mir-8-P1a Mmu-Mir-8-P1a Mom-Mir-8 Mun-Mir-8-P1a Neu-Mir-8-P1a Npo-Mir-8 Oan-Mir-8-P1a Obi-Mir-8 Ocu-Mir-8-P1a Ofu-Mir-8 Ovu-Mir-8 Pab-Mir-8-P1a Pau-Mir-8 Pbv-Mir-8-P1a Pca-Mir-8 Pdu-Mir-8 Pfl-Mir-8 Pmi-Mir-8 Pve-Mir-8 Rno-Mir-8-P1a Rph-Mir-8 Sha-Mir-8-P1a Sko-Mir-8 Sma-Mir-8 Snu-Mir-8 Spt-Mir-8-P1a Spu-Mir-8 Tca-Mir-8 Tgu-Mir-8-P1a Tni-Mir-8-P1a Tur-Mir-8 War-Mir-8 Xla-Mir-8-P1a1 Xla-Mir-8-P1a2 Xtr-Mir-8-P1a

Node of Origin (locus)

Vertebrata

Node of Origin (family)

Nephrozoa

Genome context
(GCA_003427355_STO_add)

BFAA01000031.1: 1278868-1278926 [+]

Clustered miRNAs
(< 50kb from Mir-8-P1a)

Mir-8-P1a BFAA01000031.1: 1278868-1278926 [+]
Mir-8-P2a BFAA01000031.1: 1281806-1281866 [+]
Mir-8-P3a BFAA01000031.1: 1291984-1292042 [+]

Seed

AAUACUG

Precursor
(pre-Mir +30nt flank)

AACAAUGAAAGAUUUUUGGGGAGGUAUUGUCAUCUUACUGGGCAGCAUUGGAUGUAACUGGUAUUCUAAUACUGCCUGGUAAUGAUGAUGAUGGCUUUCUGAUUUCAUCGGAGAAGAAU

Get precursor sequence

Structure

        10          20        30         40        50        
AACAAUGAAAGAUUUUU--  GG  G   UG     -|   UG     C      UGUAA 
                   GG  AG UAU  UCAUC UUAC  GGCAG AUUGGA     C
                   UC  UC GUA  AGUAG AAUG  CCGUC UAAUCU     U
UAAGAAGAGGCUACUUUAG  UU  G   GU     U^   GU     A      UAUGG 
       110       100        90        80        70        60

Deep sequencing

Go to detailed chart

Comment

There is a second Drosha cut +1 on both arms.

3' NTU

Motifs

UG at 5p(-14), CNNC at 3p(+17), UGUG in loop

Tissue expression

To

Star sequence

Sto-Mir-8-P1a_5p*

mirBase accession

None

Sequence

0- CAUCUUACUGGGCAGCAUUGGA -22

Get sequence

Mature sequence

Sto-Mir-8-P1a_3p

mirBase accession

None

Sequence

36- UAAUACUGCCUGGUAAUGAUGAU -59

Get sequence