Mir-451

MirGeneDB ID

Mmu-Mir-451

Family name

MIR-451 (all species)

Species

House mouse (Mus musculus)

MiRBase ID

mmu-mir-451a

Paralogues

Orthologues

Aca-Mir-451 Ami-Mir-451 Bta-Mir-451 Cfa-Mir-451 Cja-Mir-451 Cli-Mir-451 Cmi-Mir-451 Cpi-Mir-451 Cpo-Mir-451 Dno-Mir-451 Dre-Mir-451 Ebu-Mir-451 Eca-Mir-451 Ete-Mir-451 Gga-Mir-451 Gja-Mir-451 Gmo-Mir-451 Hsa-Mir-451 Laf-Mir-451 Lch-Mir-451 Loc-Mir-451 Mal-Mir-451 Mdo-Mir-451 Mml-Mir-451 Mmr-Mir-451 Mun-Mir-451 Neu-Mir-451 Oan-Mir-451 Ocu-Mir-451 Pab-Mir-451 Pma-Mir-451 Rno-Mir-451 Sha-Mir-451 Spt-Mir-451 Sto-Mir-451 Tgu-Mir-451 Tni-Mir-451 Xla-Mir-451-P1 Xla-Mir-451-P2 Xtr-Mir-451

Node of Origin (locus)

Vertebrata

Node of Origin (family)

Vertebrata

Genome context
(mm10)

chr11: 78073186-78073227 [+] UCSC Ensembl

Clustered miRNAs
(< 50kb from Mir-451)

Mir-144-v1 chr11: 78073010-78073067 [+] UCSC Ensembl
Mir-144-v2 chr11: 78073010-78073067 [+] UCSC Ensembl
Mir-451 chr11: 78073186-78073227 [+] UCSC Ensembl

Seed

AACCGUU

Precursor
(pre-Mir +30nt flank)

UGACAGCUGUGGCACUUGGGAAUGGCGAGGAAACCGUUACCAUUACUGAGUUUAGUAAUGGUAACGGUUCUCUUGCUGCUCCCACAAACUGUGCCAAGAAGA

Get precursor sequence

Structure

        10          20        30        40        50
UGACAGCUGUGGCACUU--|   AU      GA                 A 
                   GGGA  GGCGAG  AACCGUUACCAUUACUG G
                   CCCU  UCGUUC  UUGGCAAUGGUAAUGAU U
AGAAGAACCGUGUCAAACA^   CG      UC                 U 
100        90        80        70        60

Deep sequencing

Go to detailed chart

Comment

As a non-canonical (Group 4, Kim et al. 2016) miRNA there is no discrete 3p read and the 3' end of the mature miRNA is somewhat arbitrary.

3' NTU

Motifs

UG at 5p(-14)

Tissue expression

Br	Br	Ce	Ce	Em	Em	He	Ki	Li	Lu	Ov	Pa	Sk	Sp	Te

Mature sequence

Mmu-Mir-451_5p

mirBase accession

MIMAT0001632

Sequence

0- AAACCGUUACCAUUACUGAGUU -22

Get sequence

Proposed targets

microrna.org: MIMAT0001632
TargetScanVert: mmu-miR-451a
miRDB: MIMAT0001632