MirGeneDB 3.0

MirGeneDB ID

Esc-Mir-2-o49

Family name MIR-2 (all species)
Species Hawaiian bobtail squid (Euprymna scolopes)
MiRBase ID
Paralogues Esc-Mir-2-o45-v1  Esc-Mir-2-o47a-v1  Esc-Mir-2-o47b  Esc-Mir-2-o47c  Esc-Mir-2-o47d  Esc-Mir-2-o48-v1  Esc-Mir-2-P12 
Orthologues Gsp-Mir-2  Npo-Mir-2-o49  Obi-Mir-2-o49  Ovu-Mir-2-o49  Ple-Mir-2 
Node of Origin (locus) Cephalopoda
Node of Origin (family) Protostomia
Genome context
(esc-GCA_024364805.1_ASM2436480v1)
CM044488.1: 27562752-27562815 [-] Ensembl
Clustered miRNAs
(< 50kb from Mir-2-o49)
Mir-2-o49 CM044488.1: 27562752-27562815 [-] Ensembl
Mir-2-o48-v1 CM044488.1: 27562855-27562918 [-] Ensembl
Mir-2-o48-v2 CM044488.1: 27562855-27562918 [-] Ensembl
Mir-2-o47d CM044488.1: 27563803-27563860 [-] Ensembl
Mir-2-o47c CM044488.1: 27564000-27564059 [-] Ensembl
Mir-2-o47b CM044488.1: 27564469-27564528 [-] Ensembl
Mir-2-o47a-v1 CM044488.1: 27564797-27564854 [-] Ensembl
Mir-2-o47a-v2 CM044488.1: 27564797-27564854 [-] Ensembl
Mir-2-P12 CM044488.1: 27565399-27565460 [-] Ensembl
Mir-2-o45-v1 CM044488.1: 27565591-27565650 [-] Ensembl
Mir-2-o45-v2 CM044488.1: 27565591-27565650 [-] Ensembl
Mir-71 CM044488.1: 27565864-27565922 [-] Ensembl
Seed CAUCAAA
Precursor
(pre-Mir +30nt flank)
GACUCGGCCUACAAUGGCUAGCAUCUCCUUUCAUCAAAGUGGCUGUCAUACGUUACCCUUAAUCUCAUUCGUAUCACAGCCUGCUUUGAUGAGAGGAAGCCCUUCACUACAAACCUCCACGAUG
Get precursor sequence
Structure
        10        20            30        40         50        60 
GACUCGGCCUACAAUGGCUA----| AUC               -      C     UUACCCUU 
                        GC   UCCUUUCAUCAAAGU GGCUGU AUACG        \
                        CG   AGGAGAGUAGUUUCG CCGACA UAUGC        A
GUAGCACCUCCAAACAUCACUUCC^ A--               U      C     UUACUCUA 
  120       110       100          90        80        70
Deep sequencing
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CommentIt is not clear either from phylogenetic or syntenic information how many Mir-2 genes were present in the last common ancestor of protostomes and how the multiple paralogues in lophotrochozoans relate to the four Mir-2 genes in arthropods. Thus all lophotrochozoan genes aside from Mir-2-P12 are classified as orphans pending further data and analysis.
3' NTU No
MotifsNo
Tissue expression
- +
Li
Mature sequence

Esc-Mir-2-o49_5p

mirBase accessionNone
Sequence
0- UCAUCAAAGUGGCUGUCAUACG -22
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Star sequence

Esc-Mir-2-o49_3p*

mirBase accessionNone
Sequence
41- UAUCACAGCCUGCUUUGAUGAGA -64
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