MirGeneDB 3.0

MirGeneDB ID

Npo-Mir-2-o49

Family name MIR-2 (all species)
Species Chambered Nautilus (Nautilus pompilius)
MiRBase ID
Paralogues Npo-Mir-2-o45  Npo-Mir-2-o47  Npo-Mir-2-o48a  Npo-Mir-2-o48b  Npo-Mir-2-P12 
Orthologues Esc-Mir-2-o49  Gsp-Mir-2  Obi-Mir-2-o49  Ovu-Mir-2-o49  Ple-Mir-2 
Node of Origin (locus) Cephalopoda
Node of Origin (family) Protostomia
Genome context
(GCA_018389105_NPO)
JACATO010000013.1: 410469-410530 [+] Ensembl
Clustered miRNAs
(< 50kb from Mir-2-o49)
Mir-71 JACATO010000013.1: 409153-409211 [+] Ensembl
Mir-2-o45 JACATO010000013.1: 409573-409634 [+] Ensembl
Mir-2-P12 JACATO010000013.1: 409697-409758 [+] Ensembl
Mir-2-o47 JACATO010000013.1: 409822-409878 [+] Ensembl
Mir-2-o48a JACATO010000013.1: 410153-410212 [+] Ensembl
Mir-2-o48b JACATO010000013.1: 410351-410409 [+] Ensembl
Mir-2-o49 JACATO010000013.1: 410469-410530 [+] Ensembl
Seed CAUCAAA
Precursor
(pre-Mir +30nt flank)
GCCACCCGCCGGACUGGCUGGGAUAUCCUUUCAUCAAAGUGACUGUGAUGUGUUUCAGUUUGUUAACCAUAUCACAGCCUGCUUUGAUGAGAGGAGGCCCUUUACCUCGAGGAUGGCUCUAC
Get precursor sequence
Structure
        10           20        30        40         50          
GCCACCCGCCGGACUGGCU---|  AUA                A-          UUUCAGU 
                      GGG   UCCUUUCAUCAAAGUG  CUGUGAUGUG       \
                      CCC   AGGAGAGUAGUUUCGU  GACACUAUAC       U
CAUCUCGGUAGGAGCUCCAUUU^  GG-                CC          CAAUUGU 
120       110       100         90        80        70
Deep sequencing
CommentIt is not clear either from phylogenetic or syntenic information how many Mir-2 genes were present in the last common ancestor of protostomes and how the multiple paralogues in lophotrochozoans relate to the four Mir-2 genes in arthropods. Thus all lophotrochozoan genes aside from Mir-2-P12 are classified as orphans pending further data and analysis.
3' NTU Unknown
MotifsNo
Mature sequence

Npo-Mir-2-o49_5p (predicted)

mirBase accessionNone
Sequence
0- UCAUCAAAGUGACUGUGAUGUG -22
Get sequence
Co-mature sequence

Npo-Mir-2-o49_3p (predicted)

mirBase accessionNone
Sequence
39- UAUCACAGCCUGCUUUGAUGAGA -62
Get sequence