MirGeneDB 3.0

MirGeneDB ID

Npo-Mir-2-o47

Family name MIR-2 (all species)
Species Chambered Nautilus (Nautilus pompilius)
MiRBase ID
Paralogues Npo-Mir-2-o45  Npo-Mir-2-o48a  Npo-Mir-2-o48b  Npo-Mir-2-o49  Npo-Mir-2-P12 
Orthologues Esc-Mir-2-o47a-v1  Esc-Mir-2-o47b  Esc-Mir-2-o47c  Esc-Mir-2-o47d  Gsp-Mir-2  Obi-Mir-2-o47a  Obi-Mir-2-o47b  Obi-Mir-2-o47c  Obi-Mir-2-o47d  Ovu-Mir-2-o47a  Ovu-Mir-2-o47b  Ovu-Mir-2-o47c  Ovu-Mir-2-o47d  Ple-Mir-2 
Node of Origin (locus) Cephalopoda
Node of Origin (family) Protostomia
Genome context
(GCA_018389105_NPO)
JACATO010000013.1: 409822-409878 [+] Ensembl
Clustered miRNAs
(< 50kb from Mir-2-o47)
Mir-71 JACATO010000013.1: 409153-409211 [+] Ensembl
Mir-2-o45 JACATO010000013.1: 409573-409634 [+] Ensembl
Mir-2-P12 JACATO010000013.1: 409697-409758 [+] Ensembl
Mir-2-o47 JACATO010000013.1: 409822-409878 [+] Ensembl
Mir-2-o48a JACATO010000013.1: 410153-410212 [+] Ensembl
Mir-2-o48b JACATO010000013.1: 410351-410409 [+] Ensembl
Mir-2-o49 JACATO010000013.1: 410469-410530 [+] Ensembl
Seed CACAGCC
Precursor
(pre-Mir +30nt flank)
GAGGCUGGGGAUUCAUUCGCCUCGCUGCAGAUCGUCAAGGUGGUUGUGACGUGUUGAGCCUCAUAUCACAGCCAGCUUUGAUGAGCUGGAGUGGUGUUGCAAACUGCAUUCUCUUUG
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Structure
        10            20        30        40         50       
GAGGCUGGGGAUUCAUU----|   UC   G   A         -         CG GUUG 
                     CGCC  GCU CAG UCGUCAAGG UGGUUGUGA  U    A
                     GUGG  UGA GUC AGUAGUUUC ACCGACACU  A    G
GUUUCUCUUACGUCAAACGUU^   --   G   G         G         AU CUCC 
     110       100          90        80        70        60
Deep sequencing
CommentIt is not clear either from phylogenetic or syntenic information how many Mir-2 genes were present in the last common ancestor of protostomes and how the multiple paralogues in lophotrochozoans relate to the four Mir-2 genes in arthropods. Thus all lophotrochozoan genes aside from Mir-2-P12 are classified as orphans pending further data and analysis.
3' NTU Unknown
MotifsCNNC at 3p(+17)
Star sequence

Npo-Mir-2-o47_5p* (predicted)

mirBase accessionNone
Sequence
0- AUCGUCAAGGUGGUUGUGACGUG -23
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Mature sequence

Npo-Mir-2-o47_3p (predicted)

mirBase accessionNone
Sequence
35- UCACAGCCAGCUUUGAUGAGCU -57
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