MirGeneDB 3.0

MirGeneDB ID

Esc-Mir-2-o47c

Family name MIR-2 (all species)
Species Hawaiian bobtail squid (Euprymna scolopes)
MiRBase ID
Paralogues Esc-Mir-2-o45-v1  Esc-Mir-2-o47a-v1  Esc-Mir-2-o47b  Esc-Mir-2-o47d  Esc-Mir-2-o48-v1  Esc-Mir-2-o49  Esc-Mir-2-P12 
Orthologues Gsp-Mir-2  Npo-Mir-2-o47  Obi-Mir-2-o47c  Ovu-Mir-2-o47c  Ple-Mir-2 
Node of Origin (locus) Coleoidea
Node of Origin (family) Protostomia
Genome context
(esc-GCA_024364805.1_ASM2436480v1)
CM044488.1: 27564000-27564059 [-] Ensembl
Clustered miRNAs
(< 50kb from Mir-2-o47c)
Mir-2-o49 CM044488.1: 27562752-27562815 [-] Ensembl
Mir-2-o48-v1 CM044488.1: 27562855-27562918 [-] Ensembl
Mir-2-o48-v2 CM044488.1: 27562855-27562918 [-] Ensembl
Mir-2-o47d CM044488.1: 27563803-27563860 [-] Ensembl
Mir-2-o47c CM044488.1: 27564000-27564059 [-] Ensembl
Mir-2-o47b CM044488.1: 27564469-27564528 [-] Ensembl
Mir-2-o47a-v1 CM044488.1: 27564797-27564854 [-] Ensembl
Mir-2-o47a-v2 CM044488.1: 27564797-27564854 [-] Ensembl
Mir-2-P12 CM044488.1: 27565399-27565460 [-] Ensembl
Mir-2-o45-v1 CM044488.1: 27565591-27565650 [-] Ensembl
Mir-2-o45-v2 CM044488.1: 27565591-27565650 [-] Ensembl
Mir-71 CM044488.1: 27565864-27565922 [-] Ensembl
Seed AUCACAG
Precursor
(pre-Mir +30nt flank)
AAUUUAACCUUUGACCUAAGCCGAUUGCAACUCCUCAAAGGGCUGUGAUACGCUGCCAAUAUGACAUAUCACAGCUAGCUUUGAUGAGCUGGAAUAUGGUUCUCUUGCACAUAAGUUGUC
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Structure
        10         20         30        40          50        
AAUUUAACCUUUGACCUA-     -   G  A   C      --|         CGCUGCC 
                   AGCCG AUU CA CUC UCAAAG  GGCUGUGAUA       A
                   UUGGU UAA GU GAG AGUUUC  UCGACACUAU       A
CUGUUGAAUACACGUUCUC     A   G  C   U      GA^         ACAGUAU 
.       110       100        90        80        70        60
Deep sequencing
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CommentIt is not clear either from phylogenetic or syntenic information how many Mir-2 genes were present in the last common ancestor of protostomes and how the multiple paralogues in lophotrochozoans relate to the four Mir-2 genes in arthropods. Thus all lophotrochozoan genes aside from Mir-2-P12 are classified as orphans pending further data and analysis.
3' NTU No
MotifsNo
Tissue expression
- +
Li
Star sequence

Esc-Mir-2-o47c_5p*

mirBase accessionNone
Sequence
0- CUCCUCAAAGGGCUGUGAUACG -22
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Mature sequence

Esc-Mir-2-o47c_3p

mirBase accessionNone
Sequence
36- UAUCACAGCUAGCUUUGAUGAGCU -60
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