Mir-2-o49

MirGeneDB ID

Ovu-Mir-2-o49

Family name

Species

MiRBase ID

Paralogues

Ovu-Mir-2-o45-v1 Ovu-Mir-2-o46-v1 Ovu-Mir-2-o47a Ovu-Mir-2-o47b Ovu-Mir-2-o47c Ovu-Mir-2-o47d Ovu-Mir-2-o48-v1 Ovu-Mir-2-P12

Orthologues

Esc-Mir-2-o49 Gsp-Mir-2 Npo-Mir-2-o49 Obi-Mir-2-o49 Ple-Mir-2

Node of Origin (locus)

Cephalopoda

Node of Origin (family)

Protostomia

Genome context
(GCA_003957725.1_ASM395772v1_OVU)

RXHP01057295.1: 21463-21522 [-] Ensembl

Clustered miRNAs
(< 50kb from Mir-2-o49)

Mir-2-o49 RXHP01057295.1: 21463-21522 [-] Ensembl
Mir-2-o48-v2 RXHP01057295.1: 21561-21620 [-] Ensembl
Mir-2-o48-v1 RXHP01057295.1: 21561-21620 [-] Ensembl
Mir-2-o47d RXHP01057295.1: 22007-22066 [-] Ensembl
Mir-2-o47c RXHP01057295.1: 22198-22257 [-] Ensembl
Mir-2-o47b RXHP01057295.1: 22396-22455 [-] Ensembl
Mir-2-o47a RXHP01057295.1: 22702-22761 [-] Ensembl
Mir-2-o46-v2 RXHP01057295.1: 22936-22995 [-] Ensembl
Mir-2-o46-v1 RXHP01057295.1: 22936-22995 [-] Ensembl
Mir-2-P12 RXHP01057295.1: 23087-23152 [-] Ensembl
Mir-2-o45-v1 RXHP01057295.1: 23280-23340 [-] Ensembl
Mir-2-o45-v2 RXHP01057295.1: 23280-23340 [-] Ensembl
Mir-71 RXHP01057295.1: 23544-23602 [-] Ensembl

Seed

CAUCAAA

Precursor
(pre-Mir +30nt flank)

AGACCAUACAGCGAUGGCUGGGAUCUCCUUUCAUCAAAGUGGCUGUCAUAUGCUUUCCAAUCCUUCAUAUCACAGCCUGCUUUGAUGAGAGGAAGCCCUUCACUGCAAAUUCAGAUGCCA

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Structure

        10           20        30        40         50         
AGACCAUACAGCGAUGGCU---|  AUC               -      C     CUUUCC 
                      GGG   UCCUUUCAUCAAAGU GGCUGU AUAUG      \
                      CCC   AGGAGAGUAGUUUCG CCGACA UAUAC      A
ACCGUAGACUUAAACGUCACUU^  GA-               U      C     UUCCUA 
.       110       100         90        80        70        60

Deep sequencing

Go to detailed chart

Comment

It is not clear either from phylogenetic or syntenic information how many Mir-2 genes were present in the last common ancestor of protostomes and how the multiple paralogues in lophotrochozoans relate to the four Mir-2 genes in arthropods. Thus all lophotrochozoan genes aside from Mir-2-P12 are classified as orphans pending further data and analysis.

3' NTU

Motifs

Tissue expression

Ax	Ce	Fr	He	In	Op	Op	Pe	Po	Re	Sk	St	Su	Su	Te	Ve	Vi	Wh

Mature sequence

Ovu-Mir-2-o49_5p

mirBase accession

None

Sequence

0- UCAUCAAAGUGGCUGUCAUAUG -22

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Co-mature sequence

Ovu-Mir-2-o49_3p

mirBase accession

None

Sequence

37- UAUCACAGCCUGCUUUGAUGAGA -60

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