MirGeneDB 3.0
MirGeneDB ID

Ovu-Mir-2-o48

Family name MIR-2 (all species)
Species Common octopus (Octopus vulgaris)
MiRBase ID
Paralogues Ovu-Mir-2-o45-v1  Ovu-Mir-2-o46-v1  Ovu-Mir-2-o47a  Ovu-Mir-2-o47b  Ovu-Mir-2-o47c  Ovu-Mir-2-o47d  Ovu-Mir-2-o49  Ovu-Mir-2-P12 
Orthologues Esc-Mir-2-o48-v1  Gsp-Mir-2  Npo-Mir-2-o48a  Npo-Mir-2-o48b  Obi-Mir-2-o48-v1  Ple-Mir-2 
Node of Origin (locus) Cephalopoda
Node of Origin (family) Protostomia
Genome context
(GCA_003957725.1_ASM395772v1_OVU)		 RXHP01057295.1: 21561-21620 [-] Ensembl
Clustered miRNAs
(< 50kb from Mir-2-o48-v1)		 Mir-2-o49 RXHP01057295.1: 21463-21522 [-] Ensembl
Mir-2-o48-v2 RXHP01057295.1: 21561-21620 [-] Ensembl
Mir-2-o48-v1 RXHP01057295.1: 21561-21620 [-] Ensembl
Mir-2-o47d RXHP01057295.1: 22007-22066 [-] Ensembl
Mir-2-o47c RXHP01057295.1: 22198-22257 [-] Ensembl
Mir-2-o47b RXHP01057295.1: 22396-22455 [-] Ensembl
Mir-2-o47a RXHP01057295.1: 22702-22761 [-] Ensembl
Mir-2-o46-v2 RXHP01057295.1: 22936-22995 [-] Ensembl
Mir-2-o46-v1 RXHP01057295.1: 22936-22995 [-] Ensembl
Mir-2-P12 RXHP01057295.1: 23087-23152 [-] Ensembl
Mir-2-o45-v1 RXHP01057295.1: 23280-23340 [-] Ensembl
Mir-2-o45-v2 RXHP01057295.1: 23280-23340 [-] Ensembl
Mir-71 RXHP01057295.1: 23544-23602 [-] Ensembl
Variant

Ovu-Mir-2-o48-v1
Seed CACAGCC
Precursor
(pre-Mir +30nt flank)		 
GUUGUCGGGGGCUCUGCUCUCUGCUUUAAGUCACCAAAGUGGUGGUGAUGUGUUCUCACUAAACCAUAUCACAGCCAGCUUUGAUGAGCUCAAACAUGAGACCAUACAGCGAUGGCUGGG
Get precursor sequence
Structure
        10          20         30          40        50        
GUUGUCGGGGGCUCUGC--    -  C   A  -   C     -|   G      UGUUCUC 
                   UCUC UG UUU AG UCA CAAAG UGGU GUGAUG       A
                   AGAG AC AAA UC AGU GUUUC ACCG CACUAU       C
GGGUCGGUAGCGACAUACC    U  -   C  G   A     G^   A      ACCAAAU 
.       110       100         90        80        70        60
Deep sequencing
Go to detailed chart
CommentIt is not clear either from phylogenetic or syntenic information how many Mir-2 genes were present in the last common ancestor of protostomes and how the multiple paralogues in lophotrochozoans relate to the four Mir-2 genes in arthropods. Thus all lophotrochozoan genes aside from Mir-2-P12 are classified as orphans pending further data and analysis.
3' NTU No
MotifsCNNC at 3p(+17), UGUG in loop
Tissue expression
- +
Ax Ce Fr He In Op Op Pe Po Re Sk St Su Su Te Ve Vi Wh
Star sequence

Ovu-Mir-2-o48-v1_5p*
mirBase accessionNone
Sequence 
0- UCACCAAAGUGGUGGUGAUG -20
Get sequence
Mature sequence

Ovu-Mir-2-o48-v1_3p
mirBase accessionNone
Sequence 
38- UCACAGCCAGCUUUGAUGAGCU -60
Get sequence
Variant

Ovu-Mir-2-o48-v2
Seed AUCACAG
Precursor
(pre-Mir +30nt flank)		 
GUUGUCGGGGGCUCUGCUCUCUGCUUUAAGUCACCAAAGUGGUGGUGAUGUGUUCUCACUAAACCAUAUCACAGCCAGCUUUGAUGAGCUCAAACAUGAGACCAUACAGCGAUGGCUGGG
Get precursor sequence
Structure
        10          20         30          40        50        
GUUGUCGGGGGCUCUGC--    -  C   A  -   C     -|   G        UUCUC 
                   UCUC UG UUU AG UCA CAAAG UGGU GUGAUGUG     A
                   AGAG AC AAA UC AGU GUUUC ACCG CACUAUAC     C
GGGUCGGUAGCGACAUACC    U  -   C  G   A     G^   A        CAAAU 
.       110       100         90        80        70        60
Deep sequencing
Go to detailed chart
CommentIt is not clear either from phylogenetic or syntenic information how many Mir-2 genes were present in the last common ancestor of protostomes and how the multiple paralogues in lophotrochozoans relate to the four Mir-2 genes in arthropods. Thus all lophotrochozoan genes aside from Mir-2-P12 are classified as orphans pending further data and analysis.
3' NTU No
MotifsCNNC at 3p(+17)
Tissue expression
- +
Ax Ce Fr He In Op Op Pe Po Re Sk St Su Su Te Ve Vi Wh
Star sequence

Ovu-Mir-2-o48-v2_5p*
mirBase accessionNone
Sequence 
0- UCACCAAAGUGGUGGUGAUGUG -22
Get sequence
Mature sequence

Ovu-Mir-2-o48-v2_3p
mirBase accessionNone
Sequence 
36- UAUCACAGCCAGCUUUGAUGAGCU -60
Get sequence