MirGeneDB 3.0
MirGeneDB ID

Ovu-Mir-2-o46

Family name MIR-2 (all species)
Species Common octopus (Octopus vulgaris)
MiRBase ID
Paralogues Ovu-Mir-2-o45-v1  Ovu-Mir-2-o47a  Ovu-Mir-2-o47b  Ovu-Mir-2-o47c  Ovu-Mir-2-o47d  Ovu-Mir-2-o48-v1  Ovu-Mir-2-o49  Ovu-Mir-2-P12 
Orthologues Gsp-Mir-2  Obi-Mir-2-o46-v1  Ple-Mir-2 
Node of Origin (locus) Octopus
Node of Origin (family) Protostomia
Genome context
(GCA_003957725.1_ASM395772v1_OVU)		 RXHP01057295.1: 22936-22995 [-] Ensembl
Clustered miRNAs
(< 50kb from Mir-2-o46-v1)		 Mir-2-o49 RXHP01057295.1: 21463-21522 [-] Ensembl
Mir-2-o48-v2 RXHP01057295.1: 21561-21620 [-] Ensembl
Mir-2-o48-v1 RXHP01057295.1: 21561-21620 [-] Ensembl
Mir-2-o47d RXHP01057295.1: 22007-22066 [-] Ensembl
Mir-2-o47c RXHP01057295.1: 22198-22257 [-] Ensembl
Mir-2-o47b RXHP01057295.1: 22396-22455 [-] Ensembl
Mir-2-o47a RXHP01057295.1: 22702-22761 [-] Ensembl
Mir-2-o46-v2 RXHP01057295.1: 22936-22995 [-] Ensembl
Mir-2-o46-v1 RXHP01057295.1: 22936-22995 [-] Ensembl
Mir-2-P12 RXHP01057295.1: 23087-23152 [-] Ensembl
Mir-2-o45-v1 RXHP01057295.1: 23280-23340 [-] Ensembl
Mir-2-o45-v2 RXHP01057295.1: 23280-23340 [-] Ensembl
Mir-71 RXHP01057295.1: 23544-23602 [-] Ensembl
Variant

Ovu-Mir-2-o46-v1
Seed CACAGCC
Precursor
(pre-Mir +30nt flank)		 
AUUGCCUAUUCUCUCCUAACCUUGUUACAGCUCAUCAAAGGACUGUGAUAUAUAGAUAUUUGAACGUCUCACAGCCAGCUUUGAUGAGCUGGCUGUAGGUUGCUUCCCUGCUCCGCUAGC
Get precursor sequence
Structure
        10          20        30           40        50        
AUUGCCUAUUCUCUCCU--     UGUUA            ---| A      UAUAUAGAU 
                   AACCU     CAGCUCAUCAAA   GG CUGUGA         A
                   UUGGA     GUCGAGUAGUUU   CC GACACU         U
CGAUCGCCUCGUCCCUUCG     UGUCG            CGA^ -      CUGCAAGUU 
.       110       100        90        80         70        60
Deep sequencing
Go to detailed chart
CommentIt is not clear either from phylogenetic or syntenic information how many Mir-2 genes were present in the last common ancestor of protostomes and how the multiple paralogues in lophotrochozoans relate to the four Mir-2 genes in arthropods. Thus all lophotrochozoan genes aside from Mir-2-P12 are classified as orphans pending further data and analysis.
3' NTU No
MotifsCNNC at 3p(+17)
Tissue expression
- +
Ax Ce Fr He In Op Op Pe Po Re Sk St Su Su Te Ve Vi Wh
Star sequence

Ovu-Mir-2-o46-v1_5p*
mirBase accessionNone
Sequence 
0- CUCAUCAAAGGACUGUGAUA -20
Get sequence
Mature sequence

Ovu-Mir-2-o46-v1_3p
mirBase accessionNone
Sequence 
38- UCACAGCCAGCUUUGAUGAGCU -60
Get sequence
Variant

Ovu-Mir-2-o46-v2
Seed CUCACAG
Precursor
(pre-Mir +30nt flank)		 
AUUGCCUAUUCUCUCCUAACCUUGUUACAGCUCAUCAAAGGACUGUGAUAUAUAGAUAUUUGAACGUCUCACAGCCAGCUUUGAUGAGCUGGCUGUAGGUUGCUUCCCUGCUCCGCUAGC
Get precursor sequence
Structure
        10          20        30           40        50        
AUUGCCUAUUCUCUCCU--     UGUUA            ---| A      UAUAUAGAU 
                   AACCU     CAGCUCAUCAAA   GG CUGUGA         A
                   UUGGA     GUCGAGUAGUUU   CC GACACU         U
CGAUCGCCUCGUCCCUUCG     UGUCG            CGA^ -      CUGCAAGUU 
.       110       100        90        80         70        60
Deep sequencing
Go to detailed chart
CommentIt is not clear either from phylogenetic or syntenic information how many Mir-2 genes were present in the last common ancestor of protostomes and how the multiple paralogues in lophotrochozoans relate to the four Mir-2 genes in arthropods. Thus all lophotrochozoan genes aside from Mir-2-P12 are classified as orphans pending further data and analysis.
3' NTU No
MotifsCNNC at 3p(+17)
Tissue expression
- +
Ax Ce Fr He In Op Op Pe Po Re Sk St Su Su Te Ve Vi Wh
Star sequence

Ovu-Mir-2-o46-v2_5p*
mirBase accessionNone
Sequence 
0- CUCAUCAAAGGACUGUGAUAUA -22
Get sequence
Mature sequence

Ovu-Mir-2-o46-v2_3p
mirBase accessionNone
Sequence 
36- UCUCACAGCCAGCUUUGAUGAGCU -60
Get sequence