MirGeneDB 3.0
MirGeneDB ID

Dre-Mir-146-P4

Family name MIR-146 (all species)
Species Zebrafish (Danio rerio)
MiRBase ID dre-mir-146b
Paralogues Dre-Mir-146-P1  Dre-Mir-146-P4-v1 
Orthologues Ami-Mir-146-P4  Bta-Mir-146-P4-v1  Cfa-Mir-146-P4  Cja-Mir-146-P4  Cli-Mir-146-P4  Cmi-Mir-146-P4  Cpi-Mir-146-P4  Cpo-Mir-146-P4  Dno-Mir-146-P4  Ebu-Mir-146  Eca-Mir-146-P4-v1  Gga-Mir-146-P4  Hsa-Mir-146-P4  Laf-Mir-146-P4  Lch-Mir-146-P4  Loc-Mir-146-P4  Mdo-Mir-146-P4  Mml-Mir-146-P4  Mmr-Mir-146-P4  Mmu-Mir-146-P4  Mun-Mir-146-P4  Neu-Mir-146-P4  Oan-Mir-146-P4  Ocu-Mir-146-P4  Pab-Mir-146-P4  Pma-Mir-146  Rno-Mir-146-P4  Sha-Mir-146-P4  Spt-Mir-146-P4  Sto-Mir-146-P4  Tgu-Mir-146-P4  Xla-Mir-146-P4  Xtr-Mir-146-P4 
Node of Origin (locus) Gnathostomata
Node of Origin (family) Vertebrata
Genome context
(danRer11)		 chr21: 41639989-41640049 [+] UCSC Ensembl
Clustered miRNAs
(< 50kb from Mir-146-P4-v2)		 Mir-146-P4-v2 chr21: 41639989-41640049 [+] UCSC Ensembl
Mir-146-P4-v1 chr21: 41639990-41640048 [+] UCSC Ensembl
Variant

Dre-Mir-146-P4-v2
Seed UGAGAAC
Precursor
(pre-Mir +30nt flank)		 
GCUUCUGGAUGUUACACUGAGCUCUUGGCUUUGAGAACUGAAUUCCAAGGGUGUCUGCUUUAUAUUCAGCCCACGGAGUUCAGUUCUUAAGUUUGGAUGCUCACGGCCGUCUGAACACACU
Get precursor sequence
Structure
        10         20         30        40        50        60
GCUUCUGGAUGUUACAC-     -|  UG    U              AA    GUCUGCU 
                  UGAGC UCU  GCUU GAGAACUGAAUUCC  GGGU       U
                  ACUCG AGG  UGAA UUCUUGACUUGAGG  CCCG       U
UCACACAAGUCUGCCGGC     U^  UU    -              CA    ACUUAUA 
 .       110       100        90         80        70
Deep sequencing
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CommentAlthough the terminal "T" is templated the distribution of reads (in particular the 3' offset reads) indicate that this is likely a Group 2 miRNA.
3' NTU Yes
MotifsCNNC at 3p(+17)
Tissue expression
- +
Br Br Em Ey Gu Gu He Li Li Ov Te
Mature sequence

Dre-Mir-146-P4-v2_5p
mirBase accessionMIMAT0001844
Sequence 
0- UUGAGAACUGAAUUCCAAGGGUG -23
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Proposed targets TargetScanFish: dre-miR-146b
Star sequence

Dre-Mir-146-P4-v2_3p*
mirBase accessionNone
Sequence 
40- CCACGGAGUUCAGUUCUUAAG -61
Get sequence
Variant

Dre-Mir-146-P4-v1
Seed GAGAACU
Precursor
(pre-Mir +30nt flank)		 
CUUCUGGAUGUUACACUGAGCUCUUGGCUUUGAGAACUGAAUUCCAAGGGUGUCUGCUUUAUAUUCAGCCCACGGAGUUCAGUUCUUAAGUUUGGAUGCUCACGGCCGUCUGAACACAC
Get precursor sequence
Structure
        10         20         30        40        50         
CUUCUGGAUGUUACACU-    -|  UG    U              AA    GUCUGCU 
                  GAGC UCU  GCUU GAGAACUGAAUUCC  GGGU       U
                  CUCG AGG  UGAA UUCUUGACUUGAGG  CCCG       U
CACACAAGUCUGCCGGCA    U^  UU    -              CA    ACUUAUA 
       110       100        90         80        70        60
Deep sequencing
Go to detailed chart
3' NTU No
MotifsUG at 5p(-14), CNNC at 3p(+17)
Tissue expression
- +
Br Br Em Ey Gu Gu He Li Li Ov Te
Mature sequence

Dre-Mir-146-P4-v1_5p
mirBase accessionMIMAT0001844
Sequence 
0- UGAGAACUGAAUUCCAAGGGUGU -23
Get sequence
Proposed targets TargetScanFish: dre-miR-146b
Star sequence

Dre-Mir-146-P4-v1_3p*
mirBase accessionNone
Sequence 
38- CCCACGGAGUUCAGUUCUUAA -59
Get sequence