Mir-92-o76

MirGeneDB ID

Cin-Mir-92-o76

Family name

MIR-92 (all species)

Species

Sea Squirt (Ciona intestinalis)

MiRBase ID

cin-mir-4009c

Paralogues

Cin-Mir-92-o69 Cin-Mir-92-o70 Cin-Mir-92-o71 Cin-Mir-92-o72 Cin-Mir-92-o73 Cin-Mir-92-o74 Cin-Mir-92-o75 Cin-Mir-92-o77 Cin-Mir-92-o78

Orthologues

Asu-Mir-92 Cel-Mir-92 Esc-Mir-92 Gsp-Mir-92 Hmi-Mir-92 Isc-Mir-92 Obi-Mir-92 Sme-Mir-92

Node of Origin (locus)

C. intestinalis

Node of Origin (family)

Bilateria

Genome context
(ci3)

HT000037.1: 5092-5146 [-] UCSC Ensembl

Clustered miRNAs
(< 50kb from Mir-92-o76)

Mir-92-o78 HT000037.1: 4884-4935 [-] UCSC Ensembl
Mir-92-o77 HT000037.1: 4978-5031 [-] UCSC Ensembl
Mir-92-o76 HT000037.1: 5092-5146 [-] UCSC Ensembl
Mir-92-o75 HT000037.1: 5191-5250 [-] UCSC Ensembl

Seed

AUUGCAC

Precursor
(pre-Mir +30nt flank)

UGCUACAUAUAAUAUCUGCUGUUCAUUCAUGGUACACUGAAUUGCACCAGCUUAUUAUUCUGCUAUUGCACUUUUACUGUACCCAGUAUGUUAAGCAUAUUCAACUUUCAAGAAA

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Structure

        10          20        30        40         50      
UGCUACAUAUAAUAUCU--   GUU   UCAU      C    U-|   CC   UUAU 
                   GCU   CAU    GGUACA UGAA  UGCA  AGC    U
                   CGA   GUA    CCAUGU AUUU  ACGU  UCG    A
AAAGAACUUUCAACUUAUA   AUU   UGAC      C    UC^   UA   UCUU 
   110       100        90        80        70        60

Deep sequencing

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Comment

It is not clear either from phylogenetic or syntenic information how many Mir-92 genes were present in the last common ancestor of bilaterians and how the vertebrate Mir-92s relate to the invertebrate Mir-92s and thus these multiple paralogues in invertebrates are classified here as orphans pending new data.

3' NTU

Motifs

UG at 5p(-14), CNNC at 3p(+17)

Tissue expression

C-	C-	C-	C-	C-	C-	C-	C-	C-	C-	Ga	La	La

Star sequence

Cin-Mir-92-o76_5p*

mirBase accession

None

Sequence

0- GGUACACUGAAUUGCACCAGC -21

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Mature sequence

Cin-Mir-92-o76_3p

mirBase accession

MIMAT0016505

Sequence

33- UAUUGCACUUUUACUGUACCCA -55

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