Mir-92-o74

MirGeneDB ID

Cin-Mir-92-o74

Family name

MIR-92 (all species)

Species

Sea Squirt (Ciona intestinalis)

MiRBase ID

cin-mir-92c

Paralogues

Cin-Mir-92-o69 Cin-Mir-92-o70 Cin-Mir-92-o71 Cin-Mir-92-o72 Cin-Mir-92-o73 Cin-Mir-92-o75 Cin-Mir-92-o76 Cin-Mir-92-o77 Cin-Mir-92-o78

Orthologues

Asu-Mir-92 Cel-Mir-92 Esc-Mir-92 Gsp-Mir-92 Hmi-Mir-92 Isc-Mir-92 Obi-Mir-92 Sme-Mir-92

Node of Origin (locus)

C. intestinalis

Node of Origin (family)

Bilateria

Genome context
(ci3)

3: 885439-885494 [+] UCSC Ensembl

Clustered miRNAs
(< 50kb from Mir-92-o74)

Mir-92-o72 3: 884650-884701 [+] UCSC Ensembl
Mir-92-o73 3: 884985-885041 [+] UCSC Ensembl
Mir-92-o74 3: 885439-885494 [+] UCSC Ensembl

Seed

AUUGCAC

Precursor
(pre-Mir +30nt flank)

CCCAAACUUAUAAACUGUACCUGCAUACUUAGGCCUGGCGAAGUGCAUUGCGUUGUCAUGGUCGUAUUGCACUCGUCCCGGUCUAUGUAUCUGGUAAAAACACAACGAACACGGAA

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Structure

        10           20        30         40        50       
CCCAAACUUAUAAACUG---|   UGC    U      U  -   A     U    UUGU 
                    UACC   AUAC UAGGCC GG CGA GUGCA UGCG    C
                    AUGG   UAUG AUCUGG CC GCU CACGU AUGC    A
AAGGCACAAGCAACACAAAA^   UC-    U      C  U   -     U    UGGU 
    110       100         90        80         70        60

Deep sequencing

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Comment

It is not clear either from phylogenetic or syntenic information how many Mir-92 genes were present in the last common ancestor of bilaterians and how the vertebrate Mir-92s relate to the invertebrate Mir-92s and thus these multiple paralogues in invertebrates are classified here as orphans pending new data.

3' NTU

Motifs

CNNC at 3p(+17)

Tissue expression

C-	C-	C-	C-	C-	C-	C-	C-	C-	C-	Ga	La	La

Star sequence

Cin-Mir-92-o74_5p*

mirBase accession

MIMAT0015255

Sequence

0- AGGCCUGGCGAAGUGCAUUGCGUU -24

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Mature sequence

Cin-Mir-92-o74_3p

mirBase accession

MIMAT0006098

Sequence

34- UAUUGCACUCGUCCCGGUCUAU -56

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