Mir-92-o70

MirGeneDB ID

Cin-Mir-92-o70

Family name

MIR-92 (all species)

Species

Sea Squirt (Ciona intestinalis)

MiRBase ID

cin-mir-92e

Paralogues

Cin-Mir-92-o69 Cin-Mir-92-o71 Cin-Mir-92-o72 Cin-Mir-92-o73 Cin-Mir-92-o74 Cin-Mir-92-o75 Cin-Mir-92-o76 Cin-Mir-92-o77 Cin-Mir-92-o78

Orthologues

Asu-Mir-92 Cel-Mir-92 Esc-Mir-92 Gsp-Mir-92 Hmi-Mir-92 Isc-Mir-92 Obi-Mir-92 Sme-Mir-92

Node of Origin (locus)

C. intestinalis

Node of Origin (family)

Bilateria

Genome context
(ci3)

1: 1925679-1925732 [+] UCSC Ensembl

Clustered miRNAs
(< 50kb from Mir-92-o70)

Mir-92-o69 1: 1925379-1925436 [+] UCSC Ensembl
Mir-92-o70 1: 1925679-1925732 [+] UCSC Ensembl
Mir-92-o71 1: 1926125-1926182 [+] UCSC Ensembl

Seed

AUUGCAC

Precursor
(pre-Mir +30nt flank)

CUGGUAAAACAAAACUGCGGCGCUGCAGGUCGGUGUGGGUGGGUGCAUGAAUCGUUGUGAAUUAUUGCACUUCCCUAGACUGGUCUGCUUGUCGCAUUUACUUCGAAAUUUCGG

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Structure

        10           20        30        40        50      
CUGGUAAAACAAAACUG---|    CU    GU    G    UG      UG   CGU 
                    CGGCG  GCAG  CGGU UGGG  GGUGCA  AAU   U
                    GCUGU  CGUC  GUCA AUCC  UCACGU  UUA   G
GGCUUUAAAGCUUCAUUUAC^    U-    UG    G    CU      UA   AGU 
  110       100        90         80        70        60

Deep sequencing

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Comment

It is not clear either from phylogenetic or syntenic information how many Mir-92 genes were present in the last common ancestor of bilaterians and how the vertebrate Mir-92s relate to the invertebrate Mir-92s and thus these multiple paralogues in invertebrates are classified here as orphans pending new data.

3' NTU

Motifs

CNNC at 3p(+17)

Tissue expression

C-	C-	C-	C-	C-	C-	C-	C-	C-	C-	Ga	La	La

Star sequence

Cin-Mir-92-o70_5p*

mirBase accession

MIMAT0016421

Sequence

0- CGGUGUGGGUGGGUGCAUGAAU -22

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Mature sequence

Cin-Mir-92-o70_3p

mirBase accession

MIMAT0016422

Sequence

32- UAUUGCACUUCCCUAGACUGGU -54

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