MirGeneDB 2.1

MirGeneDB ID

Mmu-Mir-145

Family name MIR-145 (all species)
Seed UCCAGUU
Species House mouse (Mus musculus)
MiRBase ID mmu-mir-145a
Paralogues
Orthologues Aca-Mir-145  Ami-Mir-145  Bta-Mir-145  Cfa-Mir-145  Cli-Mir-145  Cmi-Mir-145  Cpi-Mir-145  Cpo-Mir-145  Dno-Mir-145  Dre-Mir-145  Ebu-Mir-145  Ete-Mir-145  Gga-Mir-145  Gja-Mir-145  Gmo-Mir-145  Hsa-Mir-145  Lch-Mir-145  Loc-Mir-145  Mal-Mir-145  Mdo-Mir-145  Mml-Mir-145  Mun-Mir-145  Oan-Mir-145  Ocu-Mir-145  Pbv-Mir-145  Pma-Mir-145  Rno-Mir-145  Sha-Mir-145  Spt-Mir-145  Sto-Mir-145  Tgu-Mir-145  Xla-Mir-145-P1  Xla-Mir-145-P2  Xtr-Mir-145 
Node of Origin (locus) Vertebrata
Node of Origin (family) Vertebrata
Genome context
(mm10)
chr18: 61647829-61647888 [-] UCSC Ensembl
Clustered miRNAs
(< 50kb from Mir-145)
Mir-145 chr18: 61647829-61647888 [-] UCSC Ensembl
Mir-143 chr18: 61649199-61649253 [-] UCSC Ensembl
Precursor
(pre-Mir +30nt flank)
CAUCUCUCUCUCUCCCACCUUGUCCUCACGGUCCAGUUUUCCCAGGAAUCCCUUGGAUGCUAAGAUGGGGAUUCCUGGAAAUACUGUUCUUGAGGUCAUGGCUUAGCAGCUGGAUCUGUC
Get precursor sequence
Structure
        10          20        30        40        50          
CAUCUCUCUCUCUCCCA--| U  U     C  UC    U  C            UGGAUG 
                   CC UG CCUCA GG  CAGU UU CCAGGAAUCCCU      \
                   GG AC GGAGU UC  GUCA AA GGUCCUUAGGGG      C
CUGUCUAGGUCGACGAUUC^ U  U     -  UU    U  A            UAGAAU 
.       110       100         90        80        70
Deep sequencing
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CommentThere is a second Dicer cut -2 on both arms. Although there is a templated T at the 3' end of the 3p arm, this transcript is annotated as a Group 2 miRNA given the CAGE data in human and the 5' starting cut of 3' offset reads in various vertebrate taxa.
3' NTU Yes
MotifsCNNC at 3p(+17)
Tissue expression
 +
Bo Br Br Ce Em Em He In Ki Li Lu Mu Ov Pa Sk Sp Sp Te
Mature sequence

Mmu-Mir-145_5p

mirBase accessionMIMAT0000157
Sequence
0- GUCCAGUUUUCCCAGGAAUCCCU -23
Get sequence
Proposed targets microrna.org: MIMAT0000157
TargetScanVert: mmu-miR-145a-5p
miRDB: MIMAT0000157
Star sequence

Mmu-Mir-145_3p*

mirBase accessionMIMAT0004534
Sequence
38- GGAUUCCUGGAAAUACUGUUCU -60
Get sequence
Proposed targets microrna.org: MIMAT0004534
TargetScanVert: mmu-miR-145a-3p
miRDB: MIMAT0004534