Mir-145

MirGeneDB ID

Bta-Mir-145

Family name

MIR-145 (all species)

Seed

UCCAGUU

Species

Cow (Bos taurus)

MiRBase ID

bta-mir-145

Paralogues

Orthologues

Aca-Mir-145 Ami-Mir-145 Cfa-Mir-145 Cli-Mir-145 Cmi-Mir-145 Cpi-Mir-145 Cpo-Mir-145 Dno-Mir-145 Dre-Mir-145 Ebu-Mir-145 Ete-Mir-145 Gga-Mir-145 Gja-Mir-145 Gmo-Mir-145 Hsa-Mir-145 Lch-Mir-145 Loc-Mir-145 Mal-Mir-145 Mdo-Mir-145 Mml-Mir-145 Mmu-Mir-145 Mun-Mir-145 Oan-Mir-145 Ocu-Mir-145 Pbv-Mir-145 Pma-Mir-145 Rno-Mir-145 Sha-Mir-145 Spt-Mir-145 Sto-Mir-145 Tgu-Mir-145 Xla-Mir-145-P1 Xla-Mir-145-P2 Xtr-Mir-145

Node of Origin (locus)

Vertebrata

Node of Origin (family)

Vertebrata

Genome context
(GCF_002263795.1_ARS-UCD1.2_BTA)

NC_037334.1: 60813565-60813624 [+] UCSC Ensembl

Clustered miRNAs
(< 50kb from Mir-145)

Mir-143 NC_037334.1: 60812142-60812196 [+] UCSC Ensembl
Mir-145 NC_037334.1: 60813565-60813624 [+] UCSC Ensembl

Precursor
(pre-Mir +30nt flank)

UGAAGGCCACUCUCUCACCUUGUCCUCACGGUCCAGUUUUCCCAGGAAUCCCUUAGAUGCUAAGAUGGGGAUUCCUGGAAAUACUGUUCUUGAGGUCAUGGUUUAACAGCUGGAUUCGCC

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Structure

        10          20        30        40        50          
UGAAGGCCACUCUCUCA--| U  U     C  UC    U  C            UAGAUG 
                   CC UG CCUCA GG  CAGU UU CCAGGAAUCCCU      \
                   GG AC GGAGU UC  GUCA AA GGUCCUUAGGGG      C
CCGCUUAGGUCGACAAUUU^ U  U     -  UU    U  A            UAGAAU 
.       110       100         90        80        70

Deep sequencing

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Comment

There is a second Dicer cut -2 on both arms. Although there is a templated T at the 3' end of the 3p arm, this transcript is annotated as a Group 2 miRNA given the CAGE data in human and the 5' starting cut of 3' offset reads in various vertebrate taxa.

3' NTU

Yes

Motifs

CNNC at 3p(+17)

Tissue expression

Ad	Cd	Fe	Bo	Br	Ce	Co	Co	De	He	Hy	Ir	Ki	La	Lo	No	Op	Or	Pe	Re	Su	Te

Mature sequence

Bta-Mir-145_5p

mirBase accession

MIMAT0003542

Sequence

0- GUCCAGUUUUCCCAGGAAUCCCU -23

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Proposed targets

TargetScanVert: bta-miR-145

Star sequence

Bta-Mir-145_3p*

mirBase accession

None

Sequence

38- GGAUUCCUGGAAAUACUGUUCU -60

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