Mir-376-P2

MirGeneDB ID

Bta-Mir-376-P2

Family name

MIR-376 (all species)

Species

Cow (Bos taurus)

MiRBase ID

bta-mir-376c

Paralogues

Bta-Mir-376-P1 Bta-Mir-376-P3 Bta-Mir-376-P4 Bta-Mir-376-P5

Orthologues

Cfa-Mir-376-P2 Cja-Mir-376-P2 Cpo-Mir-376-P2 Dno-Mir-376-P2 Eca-Mir-376-P2 Ete-Mir-376-P2 Hsa-Mir-376-P2 Laf-Mir-376-P2 Mml-Mir-376-P2 Mmr-Mir-376-P2 Mmu-Mir-376-P2 Ocu-Mir-376-P2 Pab-Mir-376-P2 Rno-Mir-376-P2

Node of Origin (locus)

Eutheria

Node of Origin (family)

Eutheria

Genome context
(GCF_002263795.1_ARS-UCD1.2_BTA)

NC_037348.1: 65928963-65929020 [+] UCSC Ensembl

Clustered miRNAs
(< 50kb from Mir-376-P2)

Mir-154-P1 NC_037348.1: 65912523-65912581 [+] UCSC Ensembl
Mir-154-P2-v2 NC_037348.1: 65913749-65913806 [+] UCSC Ensembl
Mir-154-P2-v1 NC_037348.1: 65913750-65913805 [+] UCSC Ensembl
Mir-154-P3-v1 NC_037348.1: 65914212-65914266 [+] UCSC Ensembl
Mir-154-P3-v2 NC_037348.1: 65914213-65914265 [+] UCSC Ensembl
Mir-154-P4 NC_037348.1: 65915443-65915499 [+] UCSC Ensembl
Mir-154-P36 NC_037348.1: 65915604-65915659 [+] UCSC Ensembl
Mir-154-P5 NC_037348.1: 65915956-65916011 [+] UCSC Ensembl
Mir-154-P6a-v1 NC_037348.1: 65916120-65916175 [+] UCSC Ensembl
Mir-154-P6a-v2 NC_037348.1: 65916120-65916175 [+] UCSC Ensembl
Mir-154-P7 NC_037348.1: 65916418-65916475 [+] UCSC Ensembl
Mir-154-P8a NC_037348.1: 65917157-65917214 [+] UCSC Ensembl
Mir-154-P8b NC_037348.1: 65917467-65917526 [+] UCSC Ensembl
Mir-154-P9 NC_037348.1: 65920329-65920384 [+] UCSC Ensembl
Mir-154-P10 NC_037348.1: 65920673-65920729 [+] UCSC Ensembl
Mir-154-P11 NC_037348.1: 65922476-65922533 [+] UCSC Ensembl
Mir-154-P12 NC_037348.1: 65923887-65923943 [+] UCSC Ensembl
Mir-154-P35 NC_037348.1: 65925899-65925954 [+] UCSC Ensembl
Mir-376-P1 NC_037348.1: 65928589-65928648 [+] UCSC Ensembl
Mir-376-P2 NC_037348.1: 65928963-65929020 [+] UCSC Ensembl
Mir-376-P3 NC_037348.1: 65929334-65929391 [+] UCSC Ensembl
Mir-154-P14 NC_037348.1: 65929490-65929545 [+] UCSC Ensembl
Mir-376-P4 NC_037348.1: 65929716-65929773 [+] UCSC Ensembl
Mir-376-P5 NC_037348.1: 65930080-65930137 [+] UCSC Ensembl
Mir-154-P16 NC_037348.1: 65932020-65932079 [+] UCSC Ensembl
Mir-154-P17 NC_037348.1: 65933715-65933777 [+] UCSC Ensembl
Mir-154-P18 NC_037348.1: 65934207-65934264 [+] UCSC Ensembl
Mir-154-P19 NC_037348.1: 65935015-65935078 [+] UCSC Ensembl
Mir-544 NC_037348.1: 65937023-65937079 [+] UCSC Ensembl
Mir-154-P21 NC_037348.1: 65937984-65938043 [+] UCSC Ensembl
Mir-154-P22 NC_037348.1: 65940135-65940188 [+] UCSC Ensembl
Mir-154-P23 NC_037348.1: 65940523-65940580 [+] UCSC Ensembl
Mir-154-P24 NC_037348.1: 65943535-65943592 [+] UCSC Ensembl
Mir-134 NC_037348.1: 65943909-65943973 [+] UCSC Ensembl
Mir-154-P25 NC_037348.1: 65944610-65944668 [+] UCSC Ensembl
Mir-154-P6b NC_037348.1: 65945376-65945432 [+] UCSC Ensembl
Mir-154-P26 NC_037348.1: 65948700-65948757 [+] UCSC Ensembl
Mir-154-P27 NC_037348.1: 65949014-65949074 [+] UCSC Ensembl
Mir-154-P28 NC_037348.1: 65949538-65949591 [+] UCSC Ensembl
Mir-154-P29 NC_037348.1: 65951143-65951202 [+] UCSC Ensembl
Mir-541 NC_037348.1: 65953000-65953065 [+] UCSC Ensembl
Mir-3957 NC_037348.1: 65953387-65953445 [+] UCSC Ensembl
Mir-154-P30 NC_037348.1: 65953907-65953960 [+] UCSC Ensembl
Mir-154-P31 NC_037348.1: 65954052-65954107 [+] UCSC Ensembl
Mir-154-P32 NC_037348.1: 65954195-65954250 [+] UCSC Ensembl
Mir-154-P33 NC_037348.1: 65954526-65954581 [+] UCSC Ensembl
Mir-154-P6c NC_037348.1: 65955040-65955095 [+] UCSC Ensembl
Mir-154-P34 NC_037348.1: 65955342-65955398 [+] UCSC Ensembl

Seed

ACAUAGA

Precursor
(pre-Mir +30nt flank)

GGGACUAAAUCCUUCUUUGGUAUUUAAAAGGUGGAUAUUCCUUCUAUGUUUAUGUUAUUUGUGGUUAAACAUAGAGGAAAUUCCACGUUUUCAGUAUCAAAUGCUGCUUGGAAACUUU

Get precursor sequence

Structure

        10          20        30        40        50         
GGGACUAAAUCCUUCUU--|      U    G     UA     U         UGUUAU 
                   UGGUAUU AAAA GUGGA  UUCCU CUAUGUUUA      \
                   ACUAUGA UUUU CACCU  AAGGA GAUACAAAU      U
UUUCAAAGGUUCGUCGUAA^      C    G     UA     -         UGGUGU 
      110       100        90        80         70        60

Deep sequencing

Go to detailed chart

Comment

There is a second Drosha cut -1 on both arms.

3' NTU

Motifs

CNNC at 3p(+17), UGUG in loop

Tissue expression

Ad	Bo	Br	Ce	Co	Co	De	Fe	He	Hy	Ir	Ki	La	Lo	Mi	No	Op	Or	Pe	Re	Su	Te

Star sequence

Bta-Mir-376-P2_5p*

mirBase accession

MIMAT0009947

Sequence

0- GUGGAUAUUCCUUCUAUGUUUA -22

Get sequence

Proposed targets

TargetScanVert: bta-miR-376c

Mature sequence

Bta-Mir-376-P2_3p

mirBase accession

None

Sequence

37- AACAUAGAGGAAAUUCCACGU -58

Get sequence