MirGeneDB 3.0
MirGeneDB ID

Cfa-Mir-421-P1

Family name MIR-421 (all species)
Species Dog (Canis familiaris)
MiRBase ID cfa-mir-545
Paralogues Cfa-Mir-421-P2 
Orthologues Bta-Mir-421-P1-v1  Cpo-Mir-421-P1  Dno-Mir-421-P1-v1  Eca-Mir-421-P1-v1  Hsa-Mir-421-P1-v1  Mml-Mir-421-P1-v1  Mmr-Mir-421-P1a  Mmr-Mir-421-P1b  Ocu-Mir-421-P1-v1  Pab-Mir-421-P1 
Node of Origin (locus) Eutheria
Node of Origin (family) Eutheria
Genome context
(canFam3_add)		 chrX: 57590222-57590284 [-] UCSC Ensembl
Clustered miRNAs
(< 50kb from Mir-421-P1-v1)		 Mir-421-P2 chrX: 57550054-57550110 [-] UCSC Ensembl
Mir-374-P2 chrX: 57550217-57550268 [-] UCSC Ensembl
Mir-421-P1-v1 chrX: 57590222-57590284 [-] UCSC Ensembl
Mir-421-P1-v2 chrX: 57590223-57590282 [-] UCSC Ensembl
Mir-374-P1 chrX: 57590394-57590445 [-] UCSC Ensembl
Variant

Cfa-Mir-421-P1-v1
Seed CAACAAA
Precursor
(pre-Mir +30nt flank)		 
CUCCAGAGCCCAGCCUGGCACAUUAGUAGGCCUCAGUAAAUGUUUAUUGGAUGAAUAAAUGAAUGACUCAUCAACAAACAUUUAUCGUGUGCCUGCUAAGGUGAUCUCCACAGGCUCUGGACU
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Structure
        10          20        30          40        50        60 
CUCCAGAGCCCAGCCUGG--   A         CU  --|         AUUG    AAUAAAU 
                    CAC UUAGUAGGC  CA  GUAAAUGUUU    GAUG       \
                    GUG AAUCGUCCG  GU  UAUUUACAAA    CUAC       G
UCAGGUCUCGGACACCUCUA   G         U-  GC^         CAA-    UCAGUAA 
 120       110       100        90         80         70
Deep sequencing
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3' NTU No
MotifsNo
Tissue expression
- +
An An An Bl Ce Co He Hi Hi Hy Ki Ki Li Lu Ov Sk Te Te
Star sequence

Cfa-Mir-421-P1-v1_5p* (predicted)
mirBase accessionMIMAT0009911
Sequence 
0- CCUCAGUAAAUGUUUAUUGGAUG -23
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Proposed targets TargetScanVert: cfa-miR-545
miRDB: MIMAT0009911
Mature sequence

Cfa-Mir-421-P1-v1_3p
mirBase accessionNone
Sequence 
40- UCAACAAACAUUUAUCGUGUGCC -63
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Variant

Cfa-Mir-421-P1-v2
Seed UCAACAA
Precursor
(pre-Mir +30nt flank)		 
CCAGAGCCCAGCCUGGCACAUUAGUAGGCCUCAGUAAAUGUUUAUUGGAUGAAUAAAUGAAUGACUCAUCAACAAACAUUUAUCGUGUGCCUGCUAAGGUGAUCUCCACAGGCUCUGGAC
Get precursor sequence
Structure
        10           20        30          40        50         
CCAGAGCCCAGCCUGGC---  A         CU  --|         AUUG     AUAAAU 
                    AC UUAGUAGGC  CA  GUAAAUGUUU    GAUGA      \
                    UG AAUCGUCCG  GU  UAUUUACAAA    CUACU      G
CAGGUCUCGGACACCUCUAG  G         U-  GC^         CAA-     CAGUAA 
.       110       100        90         80         70        60
Deep sequencing
Go to detailed chart
3' NTU No
MotifsCNNC at 3p(+17)
Tissue expression
- +
An An An Bl Ce Co He Hi Hi Hy Ki Ki Li Lu Ov Sk Te Te
Star sequence

Cfa-Mir-421-P1-v2_5p* (predicted)
mirBase accessionMIMAT0009911
Sequence 
0- UCAGUAAAUGUUUAUUGGAUGA -22
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Proposed targets TargetScanVert: cfa-miR-545
miRDB: MIMAT0009911
Mature sequence

Cfa-Mir-421-P1-v2_3p
mirBase accessionNone
Sequence 
37- AUCAACAAACAUUUAUCGUGUGC -60
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