MirGeneDB 3.0

MirGeneDB ID

Mml-Mir-421-P1

Family name MIR-421 (all species)
Species Rhesus monkey (Macaca mulatta)
MiRBase ID mml-mir-545
Paralogues Mml-Mir-421-P2 
Orthologues Bta-Mir-421-P1-v1  Cfa-Mir-421-P1-v1  Cpo-Mir-421-P1  Dno-Mir-421-P1-v1  Eca-Mir-421-P1-v1  Hsa-Mir-421-P1-v1  Mmr-Mir-421-P1a  Mmr-Mir-421-P1b  Ocu-Mir-421-P1-v1  Pab-Mir-421-P1 
Node of Origin (locus) Eutheria
Node of Origin (family) Eutheria
Genome context
(GCA_003339765.3_Mmul_10_traces)
CM014356.1: 71376450-71376512 [-] UCSC Ensembl
Clustered miRNAs
(< 50kb from Mir-421-P1-v1)
Mir-421-P1-v1 CM014356.1: 71376450-71376512 [-] UCSC Ensembl
Mir-421-P1-v2 CM014356.1: 71376451-71376510 [-] UCSC Ensembl
Mir-374-P1 CM014356.1: 71376622-71376673 [-] UCSC Ensembl
Variant

Mml-Mir-421-P1-v1

Seed CUCAGUA
Precursor
(pre-Mir +30nt flank)
CUCCAGAGCCCAGCCUGGCACAUUAGUAGGCCUCAGUAAAUGUUUAUUAGAUGAAUAAAUGAAUGACUCAUCAGCAAACAUUUAUUGUGUGCCUGCUAAAGUGAGCUCCACAGGCUCUGGACU
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Structure
        10          20        30         40        50        60 
CUCCAGAGCCCAGCCUGG--   A         CU-|           A  A    AAUAAAU 
                    CAC UUAGUAGGC   CAGUAAAUGUUU UU GAUG       \
                    GUG AAUCGUCCG   GUUAUUUACAAA GA CUAC       G
UCAGGUCUCGGACACCUCGA   A         UGU^           C  -    UCAGUAA 
 120       110       100        90        80         70
Deep sequencing
Go to detailed chart
3' NTU No
MotifsNo
Tissue expression
- +
Bo Br Br Br He Ki Li Lu Ly Sk Sp Te Th
Mature sequence

Mml-Mir-421-P1-v1_5p

mirBase accessionNone
Sequence
0- CCUCAGUAAAUGUUUAUUAGAUG -23
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Star sequence

Mml-Mir-421-P1-v1_3p*

mirBase accessionMIMAT0006409
Sequence
40- UCAGCAAACAUUUAUUGUGUGCC -63
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Proposed targets TargetScanVert: mml-miR-545
Variant

Mml-Mir-421-P1-v2

Seed CAGUAAA
Precursor
(pre-Mir +30nt flank)
CCAGAGCCCAGCCUGGCACAUUAGUAGGCCUCAGUAAAUGUUUAUUAGAUGAAUAAAUGAAUGACUCAUCAGCAAACAUUUAUUGUGUGCCUGCUAAAGUGAGCUCCACAGGCUCUGGAC
Get precursor sequence
Structure
        10           20        30         40        50         
CCAGAGCCCAGCCUGGC---  A         CU-|           A  A     AUAAAU 
                    AC UUAGUAGGC   CAGUAAAUGUUU UU GAUGA      \
                    UG AAUCGUCCG   GUUAUUUACAAA GA CUACU      G
CAGGUCUCGGACACCUCGAG  A         UGU^           C  -     CAGUAA 
.       110       100        90        80         70        60
Deep sequencing
Go to detailed chart
3' NTU Unknown
MotifsCNNC at 3p(+17)
Tissue expression
- +
Bo Br Br Br He Ki Li Lu Ly Sk Sp Te Th
Mature sequence

Mml-Mir-421-P1-v2_5p

mirBase accessionNone
Sequence
0- UCAGUAAAUGUUUAUUAGAUGA -22
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Star sequence

Mml-Mir-421-P1-v2_3p* (predicted)

mirBase accessionMIMAT0006409
Sequence
37- AUCAGCAAACAUUUAUUGUGUGC -60
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Proposed targets TargetScanVert: mml-miR-545