MirGeneDB 3.0
MirGeneDB ID

Hsa-Mir-455

Family name MIR-455 (all species)
Species Human (Homo sapiens)
MiRBase ID hsa-mir-455
Paralogues Hsa-Mir-455-v1 
Orthologues Gja-Mir-455  Lch-Mir-455  Mun-Mir-455  Pbv-Mir-455  Pma-Mir-455  Spt-Mir-455  Xtr-Mir-455 
Node of Origin (locus) Vertebrata
Node of Origin (family) Vertebrata
Genome context
(hg38)		 chr9: 114209448-114209507 [+] UCSC Ensembl
Clustered miRNAs
(< 50kb from Mir-455-v3)		 Mir-455-v2 chr9: 114209448-114209507 [+] UCSC Ensembl
Mir-455-v3 chr9: 114209448-114209507 [+] UCSC Ensembl
Mir-455-v1 chr9: 114209449-114209506 [+] UCSC Ensembl
Variant

Hsa-Mir-455-v3
Seed GCAGUCC
Precursor
(pre-Mir +30nt flank)		 
CGAGCGCCUGCGCCCUUCCCUGGCGUGAGGGUAUGUGCCUUUGGACUACAUCGUGGAAGCCAGCACCAUGCAGUCCAUGGGCAUAUACACUUGCCUCAAGGCCUAUGUCAUCGAGGAGCC
Get precursor sequence
Structure
        10          20        30        40        50         
CGAGCGCCUGCGCCCUU--| C   C UG  G          U      A   CGUGGAA 
                   CC UGG G  AG GUAUGUGCCU UGGACU CAU       G
                   GG ACU C  UC CAUAUACGGG ACCUGA GUA       C
CCGAGGAGCUACUGUAUCC^ A   C GU  A          U      C   CCACGAC 
.       110       100        90        80        70        60
Deep sequencing
Go to detailed chart
CommentAlthough the terminal U is templated, the 3'-DcRNA reads suggest that this is Group 2 miRNA. All other vertebrates are treated accordingly.
3' NTU Yes
MotifsUGUG in loop
Tissue expression
- +
Dc Dc Dr Dr Xp Xp Bl Br Br Ce Ce Co Fo He Ki Le Li Li Lu Pa Pl Pl Sk Sk Sk Sm Sp Sp St Te Th Ut
Star sequence

Hsa-Mir-455-v3_5p*
mirBase accessionMIMAT0003150
Sequence 
0- GUAUGUGCCUUUGGACUACAUC -22
Get sequence
Proposed targets microrna.org: MIMAT0003150
TargetScanVert: hsa-miR-455-5p
TargetMiner: hsa-miR-455-5p
miRDB: MIMAT0003150
Mature sequence

Hsa-Mir-455-v3_3p
mirBase accessionMIMAT0004784
Sequence 
38- UGCAGUCCAUGGGCAUAUACAC -60
Get sequence
Proposed targets microrna.org: MIMAT0004784
TargetScanVert: hsa-miR-455-3p.1
TargetMiner: hsa-miR-455-3p
miRDB: MIMAT0004784
Variant

Hsa-Mir-455-v1
Seed AUGUGCC
Precursor
(pre-Mir +30nt flank)		 
GAGCGCCUGCGCCCUUCCCUGGCGUGAGGGUAUGUGCCUUUGGACUACAUCGUGGAAGCCAGCACCAUGCAGUCCAUGGGCAUAUACACUUGCCUCAAGGCCUAUGUCAUCGAGGAGC
Get precursor sequence
Structure
        10          20        30        40        50        
GAGCGCCUGCGCCCUUC-  -|  C UG  G          U      A   C UGGAA 
                  CC UGG G  AG GUAUGUGCCU UGGACU CAU G     G
                  GG ACU C  UC CAUAUACGGG ACCUGA GUA C     C
CGAGGAGCUACUGUAUCC  A^  C GU  A          U      C   C ACGAC 
      110       100        90        80        70        60
Deep sequencing
Go to detailed chart
3' NTU No
MotifsNo
Tissue expression
- +
Dc Dc Dr Dr Xp Xp Bl Br Br Ce Ce Co Fo He Ki Le Li Li Lu Pa Pl Pl Sk Sk Sk Sm Sp Sp St Te Th Ut
Mature sequence

Hsa-Mir-455-v1_5p
mirBase accessionMIMAT0003150
Sequence 
0- UAUGUGCCUUUGGACUACAUCG -22
Get sequence
Proposed targets microrna.org: MIMAT0003150
TargetScanVert: hsa-miR-455-5p
TargetMiner: hsa-miR-455-5p
miRDB: MIMAT0003150
Star sequence

Hsa-Mir-455-v1_3p*
mirBase accessionMIMAT0004784
Sequence 
36- AUGCAGUCCAUGGGCAUAUACA -58
Get sequence
Proposed targets microrna.org: MIMAT0004784
TargetScanVert: hsa-miR-455-3p.1
TargetMiner: hsa-miR-455-3p
miRDB: MIMAT0004784
Variant

Hsa-Mir-455-v2
Seed CAGUCCA
Precursor
(pre-Mir +30nt flank)		 
CGAGCGCCUGCGCCCUUCCCUGGCGUGAGGGUAUGUGCCUUUGGACUACAUCGUGGAAGCCAGCACCAUGCAGUCCAUGGGCAUAUACACUUGCCUCAAGGCCUAUGUCAUCGAGGAGCC
Get precursor sequence
Structure
        10          20        30        40        50         
CGAGCGCCUGCGCCCUU--| C   C UG  G          U      A   CGUGGAA 
                   CC UGG G  AG GUAUGUGCCU UGGACU CAU       G
                   GG ACU C  UC CAUAUACGGG ACCUGA GUA       C
CCGAGGAGCUACUGUAUCC^ A   C GU  A          U      C   CCACGAC 
.       110       100        90        80        70        60
Deep sequencing
Go to detailed chart
CommentAlthough the terminal U is templated, the 3'-DcRNA reads suggest that this is Group 2 miRNA. All other vertebrates are treated accordingly.
3' NTU Yes
MotifsNo
Tissue expression
- +
Dc Dc Dr Dr Xp Xp Bl Br Br Ce Ce Co Fo He Ki Le Li Li Lu Pa Pl Pl Sk Sk Sk Sm Sp Sp St Te Th Ut
Star sequence

Hsa-Mir-455-v2_5p*
mirBase accessionMIMAT0003150
Sequence 
0- GUAUGUGCCUUUGGACUACAU -21
Get sequence
Proposed targets microrna.org: MIMAT0003150
TargetScanVert: hsa-miR-455-5p
TargetMiner: hsa-miR-455-5p
miRDB: MIMAT0003150
Mature sequence

Hsa-Mir-455-v2_3p
mirBase accessionMIMAT0004784
Sequence 
39- GCAGUCCAUGGGCAUAUACAC -60
Get sequence
Proposed targets microrna.org: MIMAT0004784
TargetScanVert: hsa-miR-455-3p.1
TargetMiner: hsa-miR-455-3p
miRDB: MIMAT0004784