Let-7-P5

MirGeneDB ID

Cel-Let-7-P5

Family name

LET-7 (all species)

Species

Roundworm (Caenorhabditis elegans)

MiRBase ID

cel-let-7

Paralogues

Cel-Let-7-P6 Cel-Let-7-P7 Cel-Let-7-P8 Cel-Let-7-P9

Orthologues

Aae-Let-7 Aga-Let-7 Agr-Let-7 Asu-Let-7-P5 Bge-Let-7 Bko-Let-7 Bpl-Let-7 Cbr-Let-7-P5 Cte-Let-7 Dan-Let-7 Dlo-Let-7 Dma-Let-7 Dme-Let-7 Dmo-Let-7 Dpu-Let-7 Dsi-Let-7 Dya-Let-7 Eba-Let-7 Egr-Let-7 Esc-Let-7 Gpa-Let-7 Gsa-Let-7 Gsp-Let-7 Hme-Let-7 Hmi-Let-7 Hru-Let-7 Isc-Let-7 Lan-Let-7 Lgi-Let-7 Lhy-Let-7 Llo-Let-7 Mgi-Let-7 Mom-Let-7 Npo-Let-7 Obi-Let-7 Ofu-Let-7 Ovu-Let-7 Pau-Let-7 Pca-Let-7 Pcr-Let-7 Pdu-Let-7 Pfl-Let-7 Ple-Let-7 Pmi-Let-7 Pve-Let-7 Rph-Let-7 Sko-Let-7 Sma-Let-7 Sne-Let-7 Snu-Let-7 Spu-Let-7 Sro-Let-7 Tca-Let-7 Tur-Let-7 War-Let-7 Xbo-Let-7

Node of Origin (locus)

Chromadorea

Node of Origin (family)

Bilateria

Genome context
(ce11)

chrX: 14744191-14744255 [-] UCSC Ensembl

Seed

GAGGUAG

Precursor
(pre-Mir +30nt flank)

AUUGGUGGACGGUCUACACUGUGGAUCCGGUGAGGUAGUAGGUUGUAUAGUUUGGAAUAUUACCACCGGUGAACUAUGCAAUUUUCUACCUUACCGGAGACAGAACUCUUCGAAGCUGCGUCGUC

Get precursor sequence

Structure

        10            20        30        40        50        60  
AUUGGUGGACGGUCUACA----|   GGA             U             UGGAAUAUU 
                      CUGU   UCCGGUGAGGUAG AGGUUGUAUAGUU         \
                      GACA   AGGCCAUUCCAUC UUUAACGUAUCAA         A
CUGCUGCGUCGAAGCUUCUCAA^   G--             U             GUGGCCACC 
   120       110       100          90        80        70

Deep sequencing

Go to detailed chart

3' NTU

Motifs

Tissue expression

Da	Ea	Mi	Wi	Yo	Yo

Mature sequence

Cel-Let-7-P5_5p

mirBase accession

MIMAT0000001

Sequence

0- UGAGGUAGUAGGUUGUAUAGUU -22

Get sequence

Proposed targets

microrna.org: MIMAT0000001
TargetScanWorm: cel-let-7

Star sequence

Cel-Let-7-P5_3p*

mirBase accession

MIMAT0015091

Sequence

43- CUAUGCAAUUUUCUACCUUACC -65

Get sequence

Proposed targets

microrna.org: MIMAT0015091