Let-7-P4

MirGeneDB ID

Bfl-Let-7-P4

Family name

LET-7 (all species)

Seed

GAGGUAG

Species

Florida lancelet (Branchiostoma floridae)

MiRBase ID

bfl-let-7a-2

Paralogues

Bfl-Let-7-P3

Orthologues

Aae-Let-7 Bge-Let-7 Bla-Let-7-P4 Bpl-Let-7 Cgi-Let-7 Cte-Let-7 Dan-Let-7 Dma-Let-7 Dme-Let-7 Dmo-Let-7 Dpu-Let-7 Dsi-Let-7 Dya-Let-7 Esc-Let-7 Hme-Let-7 Isc-Let-7 Lan-Let-7 Lgi-Let-7 Npo-Let-7 Obi-Let-7 Ovu-Let-7 Pfl-Let-7 Pmi-Let-7 Sko-Let-7 Spu-Let-7 Tca-Let-7 Xbo-Let-7

Node of Origin (locus)

Branchiostoma

Node of Origin (family)

Bilateria

Genome context
(GCF_000003815.2_Bfl_VNyyK_genomic)

NC_049979.1: 15365859-15365925 [+] UCSC

Clustered miRNAs
(< 50kb from Let-7-P4)

Mir-10-P2-v1 NC_049979.1: 15363827-15363883 [+] UCSC
Mir-10-P2-v2 NC_049979.1: 15363828-15363882 [+] UCSC
Let-7-P3 NC_049979.1: 15364081-15364147 [+] UCSC
Mir-10-P3 NC_049979.1: 15365561-15365616 [+] UCSC
Let-7-P4 NC_049979.1: 15365859-15365925 [+] UCSC

Precursor
(pre-Mir +30nt flank)

GCUGGACACCAGACACGGGUGCACCUGAGGUGAGGUAGUAGGUUGUAUAGUUGAGAAGUACAUCAUUGGAGAUAACUGUGCAACCUGCUAGCUCUCCUUGGGGCAUGCCAGUUGCAGCACACCUUCC

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Structure

        10         20          30        40        50        60   
GCUGGACACCAGACACG-   --| A  UG   U   G                 GAGAAGUACA 
                  GGU  GC CC  AGG GAG UAGUAGGUUGUAUAGUU          \
                  CCG  CG GG  UCC CUC AUCGUCCAACGUGUCAA          U
CCUUCCACACGACGUUGA   UA^ -  GU   U   G                 UAGAGGUUAC 
     120       110        100        90        80        70

Deep sequencing

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3' NTU

Motifs

CNNC at 3p(+17)

Tissue expression

To

Mature sequence

Bfl-Let-7-P4_5p

mirBase accession

MIMAT0009462

Sequence

0- UGAGGUAGUAGGUUGUAUAGUU -22

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Star sequence

Bfl-Let-7-P4_3p*

mirBase accession

None

Sequence

45- CUGUGCAACCUGCUAGCUCUCC -67

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