Mir-770

MirGeneDB ID

Hsa-Mir-770

Family name

MIR-770 (all species)

Species

Human (Homo sapiens)

MiRBase ID

hsa-mir-770

Paralogues

Orthologues

Cja-Mir-770 Eca-Mir-770 Mml-Mir-770 Mmr-Mir-770 Mmu-Mir-770 Pab-Mir-770 Rno-Mir-770

Node of Origin (locus)

Boreoeutheria

Node of Origin (family)

Boreoeutheria

Genome context
(hg38)

chr14: 100852409-100852470 [+] UCSC Ensembl

Clustered miRNAs
(< 50kb from Mir-770)

Mir-770 chr14: 100852409-100852470 [+] UCSC Ensembl
Mir-493 chr14: 100869075-100869136 [+] UCSC Ensembl
Mir-337-as chr14: 100874513-100874572 [-] UCSC Ensembl
Mir-337-v2 chr14: 100874515-100874574 [+] UCSC Ensembl
Mir-337-v1 chr14: 100874515-100874574 [+] UCSC Ensembl
Mir-431 chr14: 100881026-100881089 [+] UCSC Ensembl
Mir-433 chr14: 100881897-100881970 [+] UCSC Ensembl
Mir-127 chr14: 100883001-100883056 [+] UCSC Ensembl
Mir-432 chr14: 100884496-100884564 [+] UCSC Ensembl
Mir-136-v2 chr14: 100884716-100884771 [+] UCSC Ensembl
Mir-136-v1 chr14: 100884716-100884771 [+] UCSC Ensembl

Seed

CCAGUAC

Precursor
(pre-Mir +30nt flank)

AUUCAUGUGUCAGGAGCCACCUUCCGAGCCUCCAGUACCACGUGUCAGGGCCACAUGAGCUGGGCCUCGUGGGCCUGAUGUGGUGCUGGGGCCUCAGGGGUCUGCUCUUCUUCUCUUUCAGA

Get precursor sequence

Structure

        10           20        30        40        50        60 
AUUCAUGUGUCAGGAGCC---|    CC   C            GU      G    AUGAGC 
                     ACCUU  GAG CUCCAGUACCAC  GUCAGG CCAC      U
                     UGGGG  CUC GGGGUCGUGGUG  UAGUCC GGUG      G
AGACUUUCUCUUCUUCUCGUC^    A-   C            --      G    CUCCGG 
120       110       100         90        80          70

Deep sequencing

Go to detailed chart

Comment

The Drosha cut is -3 relative to the murids and Microcebus.

3' NTU

Motifs

CNNC at 3p(+17)

Tissue expression

Dc	Dc	Dr	Dr	Xp	Xp	Bl	Br	Br	Ce	Ce	Co	Fo	He	Ki	Le	Li	Li	Lu	Pa	Pl	Pl	Sk	Sk	Sk	Sm	Sp	Sp	St	Te	Th	Ut

Mature sequence

Hsa-Mir-770_5p

mirBase accession

MIMAT0003948

Sequence

0- UCCAGUACCACGUGUCAGGGCCACA -25

Get sequence

Proposed targets

microrna.org: MIMAT0003948
TargetScanVert: hsa-miR-770-5p
TargetMiner: hsa-miR-770-5p
miRDB: MIMAT0003948

Star sequence

Hsa-Mir-770_3p*

mirBase accession

None

Sequence

39- UGGGCCUGAUGUGGUGCUGGGGC -62

Get sequence