Mir-2-o137

MirGeneDB ID

Egr-Mir-2-o137

Family name

MIR-2 (all species)

Species

Hydatid worm (Echinococcus granulosus)

MiRBase ID

egr-mir-2b

Paralogues

Egr-Mir-2-o136 Egr-Mir-2-o138

Orthologues

Gsp-Mir-2 Ple-Mir-2

Node of Origin (locus)

E. granulosus

Node of Origin (family)

Protostomia

Genome context
(GCA_000524195.1_ASM52419v1_Egranulosus)

APAU02000027.1: 925765-925820 [+] UCSC Ensembl

Clustered miRNAs
(< 50kb from Mir-2-o137)

Mir-71 APAU02000027.1: 925561-925620 [+] UCSC Ensembl
Mir-2-o136 APAU02000027.1: 925661-925716 [+] UCSC Ensembl
Mir-2-o137 APAU02000027.1: 925765-925820 [+] UCSC Ensembl

Seed

AUCACAG

Precursor
(pre-Mir +30nt flank)

CGGUUUUUUUGCUCUUUUGCUGUCAGUCGGUGUCCCAAGGGUGGUGAUCUACUCAGUGGGAGUAUCACAGCCCUGCUUGGGACACAUGCUGGCAGCUCGAACGACCGAAUUUCACC

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Structure

        10          20        30           40        50       
CGGUUUUUUUGCUCUUUU--         CG        ---|    G    UC    CAG 
                    GCUGUCAGU  GUGUCCCA   AGGGU GUGA  UACU   \
                    CGACGGUCG  CACAGGGU   UCCCG CACU  AUGA   U
CCACUUUAAGCCAGCAAGCU         UA        UCG^    A    --    GGG 
    110       100        90        80        70          60

Deep sequencing

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Comment

It is not clear either from phylogenetic or syntenic information how many Mir-2 genes were present in the last common ancestor of protostomes and how the multiple paralogues in lophotrochozoans relate to the four Mir-2 genes in arthropods. Thus all lophotrochozoan genes aside from Mir-2-P12 are classified as orphans pending further data and analysis.

3' NTU

Motifs

CNNC at 3p(+17)

Tissue expression

Eg	Eg	Ev	Ev	Ad	Fe	Fe	Hy	Hy	Hy	Li	Li	Li	Mi	Mi	Mi	Po	Po	Po	Po	Po	Po	Po	Pr	Pr	Pr	Sm

Star sequence

Egr-Mir-2-o137_5p*

mirBase accession

MIMAT0037420

Sequence

0- UGUCCCAAGGGUGGUGAUCUACU -23

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Mature sequence

Egr-Mir-2-o137_3p

mirBase accession

MIMAT0020230

Sequence

32- UAUCACAGCCCUGCUUGGGACACA -56

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