Mir-2-o90

MirGeneDB ID

Eba-Mir-2-o90

Family name

MIR-2 (all species)

Species

Epimenia (Solenogaster) (Epimenia babai)

MiRBase ID

Paralogues

Eba-Mir-2-o91 Eba-Mir-2-o92

Orthologues

Gsp-Mir-2 Ple-Mir-2

Node of Origin (locus)

E. babai

Node of Origin (family)

Protostomia

Genome context
(GCA_011762755.2_ASM1176275v2_Epimenia)

WURV02085510.1: 1105-1165 [+] Ensembl

Clustered miRNAs
(< 50kb from Mir-2-o90)

Mir-2-o90 WURV02085510.1: 1105-1165 [+] Ensembl
Mir-2-o91 WURV02085510.1: 2691-2749 [+] Ensembl
Mir-2-o92 WURV02085510.1: 3976-4035 [+] Ensembl

Seed

AUCACAG

Precursor
(pre-Mir +30nt flank)

AUUUAUGAUGACUCGAGCAUUCCUGGUGGAUCGUCAAAGUUUCUGUGAAAUGUGUCAUAUAUUCAUCAUAUCACAGUCAGCUUUGACGAGCCUCCGUGGGUGUCCAAUCAGCCGCCUCACA

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Structure

        10          20        30        40         50         
AUUUAUGAUGACUCGAG--     C   U  A           U-|     A   UGUCAU 
                   CAUUC UGG GG UCGUCAAAGUU  CUGUGA AUG      A
                   GUGGG GCC CC AGCAGUUUCGA  GACACU UAC      U
ACACUCCGCCGACUAACCU     U   U  G           CU^     A   UACUUA 
 .       110       100        90        80        70        60

Deep sequencing

Comment

It is not clear either from phylogenetic or syntenic information how many Mir-2 genes were present in the last common ancestor of protostomes and how the multiple paralogues in lophotrochozoans relate to the four Mir-2 genes in arthropods. Thus all lophotrochozoan genes aside from Mir-2-P12 are classified as orphans pending further data and analysis.

3' NTU

Motifs

CNNC at 3p(+17), UGUG in loop

Tissue expression

To

Star sequence

Eba-Mir-2-o90_5p* (predicted)

mirBase accession

None

Sequence

0- UCGUCAAAGUUUCUGUGAAAUG -22

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Mature sequence

Eba-Mir-2-o90_3p (predicted)

mirBase accession

None

Sequence

38- UAUCACAGUCAGCUUUGACGAGC -61

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