MirGeneDB 3.0
MirGeneDB ID

Snu-Mir-2-o42

Family name MIR-2 (all species)
Species Peanut worm (Sipunculus nudus)
MiRBase ID
Paralogues Snu-Mir-2-o40-v1  Snu-Mir-2-o41  Snu-Mir-2-o43  Snu-Mir-2-o44 
Orthologues Gsp-Mir-2  Ple-Mir-2 
Node of Origin (locus) S. nudus
Node of Origin (family) Protostomia
Genome context
(GCA_026874595.1_ASM2687459v1_Sipunculus_nudus)		 CM049316.1: 13594492-13594547 [+]
Clustered miRNAs
(< 50kb from Mir-2-o42-v1)		 Mir-71 CM049316.1: 13592864-13592924 [+]
Mir-2-o40-v2 CM049316.1: 13593314-13593376 [+]
Mir-2-o40-v1 CM049316.1: 13593316-13593374 [+]
Mir-2-o41 CM049316.1: 13593873-13593932 [+]
Mir-2-o42-v2 CM049316.1: 13594489-13594550 [+]
Mir-2-o42-v1 CM049316.1: 13594492-13594547 [+]
Mir-2-o43 CM049316.1: 13595017-13595073 [+]
Mir-2-o44 CM049316.1: 13596008-13596064 [+]
Variant

Snu-Mir-2-o42-v1
Seed AUCACAG
Precursor
(pre-Mir +30nt flank)		 
CAUAAGUGGGAUUUGCCAGUUGACCAGAGCAUCAUAGUGGCUGUGAUGUGCGGUGAUCAGGACAUAUCACAGCCAGCUUUGAUGAGCCUGGUCGGGAGGCAUCAUCAGCACAAGUC
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Structure
        10          20         30         40        50      
CAUAAGUGGGAUUUGCCAG--        AG-     U  -|            CGGUG 
                     UUGACCAG   CAUCA AG UGGCUGUGAUGUG     A
                     GGCUGGUC   GUAGU UC ACCGACACUAUAC     U
CUGAACACGACUACUACGGAG        CGA     U  G^            AGGAC 
    110       100        90        80        70        60
Deep sequencing
Go to detailed chart
CommentIt is not clear either from phylogenetic or syntenic information how many Mir-2 genes were present in the last common ancestor of protostomes and how the multiple paralogues in lophotrochozoans relate to the four Mir-2 genes in arthropods. Thus all lophotrochozoan genes aside from Mir-2-P12 are classified as orphans pending further data and analysis.
3' NTU No
MotifsCNNC at 3p(+17)
Tissue expression
- +
To
Star sequence

Snu-Mir-2-o42-v1_5p* (predicted)
mirBase accessionNone
Sequence 
0- AUCAUAGUGGCUGUGAUGUG -20
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Mature sequence

Snu-Mir-2-o42-v1_3p
mirBase accessionNone
Sequence 
34- UAUCACAGCCAGCUUUGAUGAG -56
Get sequence
Variant

Snu-Mir-2-o42-v2
Seed CACAGCC
Precursor
(pre-Mir +30nt flank)		 
UGUCAUAAGUGGGAUUUGCCAGUUGACCAGAGCAUCAUAGUGGCUGUGAUGUGCGGUGAUCAGGACAUAUCACAGCCAGCUUUGAUGAGCCUGGUCGGGAGGCAUCAUCAGCACAAGUCCAU
Get precursor sequence
Structure
        10          20        30         40         50         
UGUCAUAAGUGGGAUUU--   AG        AG-     U  -|          UGCGGUG 
                   GCC  UUGACCAG   CAUCA AG UGGCUGUGAUG       A
                   CGG  GGCUGGUC   GUAGU UC ACCGACACUAU       U
UACCUGAACACGACUACUA   AG        CGA     U  G^          ACAGGAC 
120       110       100        90        80        70        60
Deep sequencing
Go to detailed chart
CommentIt is not clear either from phylogenetic or syntenic information how many Mir-2 genes were present in the last common ancestor of protostomes and how the multiple paralogues in lophotrochozoans relate to the four Mir-2 genes in arthropods. Thus all lophotrochozoan genes aside from Mir-2-P12 are classified as orphans pending further data and analysis.
3' NTU No
MotifsUG at 5p(-14), CNNC at 3p(+17)
Tissue expression
- +
To
Star sequence

Snu-Mir-2-o42-v2_5p* (predicted)
mirBase accessionNone
Sequence 
0- AGCAUCAUAGUGGCUGUGAUG -21
Get sequence
Mature sequence

Snu-Mir-2-o42-v2_3p
mirBase accessionNone
Sequence 
39- UCACAGCCAGCUUUGAUGAGCCU -62
Get sequence