MirGeneDB 3.0

MirGeneDB ID

Snu-Mir-2-o40

Family name MIR-2 (all species)
Species Peanut worm (Sipunculus nudus)
MiRBase ID
Paralogues Snu-Mir-2-o41  Snu-Mir-2-o42-v1  Snu-Mir-2-o43  Snu-Mir-2-o44 
Orthologues Gsp-Mir-2  Ple-Mir-2 
Node of Origin (locus) S. nudus
Node of Origin (family) Protostomia
Genome context
(GCA_026874595.1_ASM2687459v1_Sipunculus_nudus)
CM049316.1: 13593316-13593374 [+]
Clustered miRNAs
(< 50kb from Mir-2-o40-v1)
Mir-71 CM049316.1: 13592864-13592924 [+]
Mir-2-o40-v2 CM049316.1: 13593314-13593376 [+]
Mir-2-o40-v1 CM049316.1: 13593316-13593374 [+]
Mir-2-o41 CM049316.1: 13593873-13593932 [+]
Mir-2-o42-v2 CM049316.1: 13594489-13594550 [+]
Mir-2-o42-v1 CM049316.1: 13594492-13594547 [+]
Mir-2-o43 CM049316.1: 13595017-13595073 [+]
Mir-2-o44 CM049316.1: 13596008-13596064 [+]
Variant

Snu-Mir-2-o40-v1

Seed AUCACAG
Precursor
(pre-Mir +30nt flank)
AAUGCUCCGCUAAGUUAUGGUGUGCCUGGGCGUCAAUGCUGGAUGUAGUAGUCAAUGAUGGAAGUUCUAUCACAGCCAGCUUUGAUGAGCCAGGACAACCUGUCAGCAUCACCGGCAUC
Get precursor sequence
Structure
        10         20        30         40        50         
AAUGCUCCGCUAAGUUAU-   GUG     G-|     U     A   A    UCAAUGA 
                   GGU   CCUGG  CGUCAA GCUGG UGU GUAG       \
                   CCA   GGACC  GUAGUU CGACC ACA UAUC       U
CUACGGCCACUACGACUGU   ACA     GA^     U     G   C    UUGAAGG 
       110       100        90        80        70        60
Deep sequencing
Go to detailed chart
3' NTU No
MotifsCNNC at 3p(+17)
Tissue expression
- +
To
Star sequence

Snu-Mir-2-o40-v1_5p* (predicted)

mirBase accessionNone
Sequence
0- CGUCAAUGCUGGAUGUAGUAGU -22
Get sequence
Mature sequence

Snu-Mir-2-o40-v1_3p

mirBase accessionNone
Sequence
37- UAUCACAGCCAGCUUUGAUGAG -59
Get sequence
Variant

Snu-Mir-2-o40-v2

Seed CACAGCC
Precursor
(pre-Mir +30nt flank)
GGAAUGCUCCGCUAAGUUAUGGUGUGCCUGGGCGUCAAUGCUGGAUGUAGUAGUCAAUGAUGGAAGUUCUAUCACAGCCAGCUUUGAUGAGCCAGGACAACCUGUCAGCAUCACCGGCAUCAG
Get precursor sequence
Structure
        10        20         30         40        50        60 
GGAAUGCUCCGCUAAGUUAU-   GUG     G-|     U     A   A   GUCAAUGA 
                     GGU   CCUGG  CGUCAA GCUGG UGU GUA        \
                     CCA   GGACC  GUAGUU CGACC ACA UAU        U
GACUACGGCCACUACGACUGU   ACA     GA^     U     G   C   CUUGAAGG 
 120       110       100        90        80        70
Deep sequencing
Go to detailed chart
CommentIt is not clear either from phylogenetic or syntenic information how many Mir-2 genes were present in the last common ancestor of protostomes and how the multiple paralogues in lophotrochozoans relate to the four Mir-2 genes in arthropods. Thus all lophotrochozoan genes aside from Mir-2-P12 are classified as orphans pending further data and analysis.
3' NTU No
MotifsCNNC at 3p(+17)
Tissue expression
- +
To
Star sequence

Snu-Mir-2-o40-v2_5p* (predicted)

mirBase accessionNone
Sequence
0- GGCGUCAAUGCUGGAUGUAGUA -22
Get sequence
Mature sequence

Snu-Mir-2-o40-v2_3p

mirBase accessionNone
Sequence
41- UCACAGCCAGCUUUGAUGAGCC -63
Get sequence