MirGeneDB 3.0
MirGeneDB ID

Sme-Mir-2-o122b

Family name MIR-2 (all species)
Species Freshwater planarian (Schmidtea mediterranea)
MiRBase ID sme-mir-2a-2
Paralogues Sme-Mir-2-o122a  Sme-Mir-2-o123  Sme-Mir-2-o124  Sme-Mir-2-o125  Sme-Mir-2-o126  Sme-Mir-2-o127  Sme-Mir-2-o128  Sme-Mir-2-o129 
Orthologues Gsp-Mir-2  Ple-Mir-2 
Node of Origin (locus) S. mediterranea
Node of Origin (family) Protostomia
Genome context
(Sme_GCA_002600895.1_ASM260089v1_alt)		 NNSW01000001_dd_Smes_g4_1: 13481745-13481799 [+] UCSC Ensembl
Clustered miRNAs
(< 50kb from Mir-2-o122b)		 Mir-71-o1b NNSW01000001_dd_Smes_g4_1: 13481649-13481705 [+] UCSC Ensembl
Mir-2-o122b NNSW01000001_dd_Smes_g4_1: 13481745-13481799 [+] UCSC Ensembl
Seed AUCACAG
Precursor
(pre-Mir +30nt flank)		 
GAUGGUCAUCAUAAUUGUUCACUUAAUUGAGUUCUACGGUGUUGUGAUAUAAUGAUUAUUUAUAUCACAGCCCCGCUUGGAACGCUAAAAUAUGAAUGUUCAUCAUUAAUUACAU
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Structure
        10          20        30          40        50      
GAUGGUCAUCAUAAUUG--    CUUAAUUGA      --|  U           AUGA 
                   UUCA         GUUCUA  CGG GUUGUGAUAUA    \
                   AAGU         CAAGGU  GCC CGACACUAUAU    U
UACAUUAAUUACUACUUGU    AUAAAAUCG      UC^  C           UUAU 
   110       100        90        80        70        60
Deep sequencing
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CommentIt is not clear either from phylogenetic or syntenic information how many Mir-2 genes were present in the last common ancestor of protostomes and how the multiple paralogues in lophotrochozoans relate to the four Mir-2 genes in arthropods. Thus all lophotrochozoan genes aside from Mir-2-P12 are classified as orphans pending further data and analysis.
3' NTU No
MotifsCNNC at 3p(+17)
Tissue expression
- +
Ag Ag Di Gf Ne Ph Se Se Se Se Se Se Se Se Se Se Se Wh Wh Wh
Star sequence

Sme-Mir-2-o122b_5p*
mirBase accessionMIMAT0012093
Sequence 
0- GUUCUACGGUGUUGUGAUAUA -21
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Mature sequence

Sme-Mir-2-o122b_3p
mirBase accessionMIMAT0003963
Sequence 
32- UAUCACAGCCCCGCUUGGAACGC -55
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