MirGeneDB 3.0

MirGeneDB ID

Pve-Mir-2-o76

Family name MIR-2 (all species)
Species Vernerds tusk shell (Pictodentalium vernedei)
MiRBase ID
Paralogues Pve-Mir-2-o74-v1  Pve-Mir-2-o75-v1  Pve-Mir-2-o77  Pve-Mir-2-o78-v1  Pve-Mir-2-o79  Pve-Mir-2-P12 
Orthologues Gsp-Mir-2  Ple-Mir-2 
Node of Origin (locus) Dentaliidae
Node of Origin (family) Protostomia
Genome context
(Pve_genome_chr_only)
Pve_Chr8: 484550545-484550603 [-] Ensembl
Clustered miRNAs
(< 50kb from Mir-2-o76-v1)
Mir-2-o79 Pve_Chr8: 484544223-484544280 [-] Ensembl
Mir-2-o78-v2 Pve_Chr8: 484544606-484544663 [-] Ensembl
Mir-2-o78-v1 Pve_Chr8: 484544606-484544663 [-] Ensembl
Mir-2-o77 Pve_Chr8: 484550374-484550431 [-] Ensembl
Mir-2-o76-v1 Pve_Chr8: 484550545-484550603 [-] Ensembl
Mir-2-o76-v2 Pve_Chr8: 484550545-484550603 [-] Ensembl
Mir-2-o75-v2 Pve_Chr8: 484566363-484566425 [-] Ensembl
Mir-2-o75-v1 Pve_Chr8: 484566363-484566425 [-] Ensembl
Mir-2-P12 Pve_Chr8: 484566495-484566554 [-] Ensembl
Mir-2-o74-v2 Pve_Chr8: 484570188-484570248 [-] Ensembl
Mir-2-o74-v1 Pve_Chr8: 484570189-484570248 [-] Ensembl
Mir-71 Pve_Chr8: 484570428-484570486 [-] Ensembl
Variant

Pve-Mir-2-o76-v1

Seed AUCACAG
Precursor
(pre-Mir +30nt flank)
ACCACUUGAAGAAAAAAAGUUUGCUUGUAGUCGUCAAAGUGGCAGUGAAAUGUGGAGAUAAGUUCAUAUCACAGCCAGCUUUGAUGAGCUUUUGGCUAACAAAAUGCACCAAGACAGCA
Get precursor sequence
Structure
        10         20        30          40        50        
ACCACUUGAAGAAAAAAA-   U   UGU  -         -|   A    A   UGGAG 
                   GUU GCU   AG UCGUCAAAG UGGC GUGA AUG     A
                   CAA CGG   UC AGUAGUUUC ACCG CACU UAC     U
ACGACAGAACCACGUAAAA   U   UUU  G         G^   A    A   UUGAA 
       110       100        90        80        70        60
Deep sequencing
Go to detailed chart
CommentIt is not clear either from phylogenetic or syntenic information how many Mir-2 genes were present in the last common ancestor of protostomes and how the multiple paralogues in lophotrochozoans relate to the four Mir-2 genes in arthropods. Thus all lophotrochozoan genes aside from Mir-2-P12 are classified as orphans pending further data and analysis.
3' NTU No
MotifsCNNC at 3p(+17)
Tissue expression
- +
To
Star sequence

Pve-Mir-2-o76-v1_5p*

mirBase accessionNone
Sequence
0- UCGUCAAAGUGGCAGUGAAAUG -22
Get sequence
Mature sequence

Pve-Mir-2-o76-v1_3p

mirBase accessionNone
Sequence
36- UAUCACAGCCAGCUUUGAUGAGC -59
Get sequence
Variant

Pve-Mir-2-o76-v2

Seed CACAGCC
Precursor
(pre-Mir +30nt flank)
ACCACUUGAAGAAAAAAAGUUUGCUUGUAGUCGUCAAAGUGGCAGUGAAAUGUGGAGAUAAGUUCAUAUCACAGCCAGCUUUGAUGAGCUUUUGGCUAACAAAAUGCACCAAGACAGCA
Get precursor sequence
Structure
        10         20        30          40        50        
ACCACUUGAAGAAAAAAA-   U   UGU  -         -|   A    AAUGUGGAG 
                   GUU GCU   AG UCGUCAAAG UGGC GUGA         A
                   CAA CGG   UC AGUAGUUUC ACCG CACU         U
ACGACAGAACCACGUAAAA   U   UUU  G         G^   A    AUACUUGAA 
       110       100        90        80        70        60
Deep sequencing
Go to detailed chart
CommentIt is not clear either from phylogenetic or syntenic information how many Mir-2 genes were present in the last common ancestor of protostomes and how the multiple paralogues in lophotrochozoans relate to the four Mir-2 genes in arthropods. Thus all lophotrochozoan genes aside from Mir-2-P12 are classified as orphans pending further data and analysis.
3' NTU No
MotifsCNNC at 3p(+17), UGUG in loop
Tissue expression
- +
To
Star sequence

Pve-Mir-2-o76-v2_5p*

mirBase accessionNone
Sequence
0- UCGUCAAAGUGGCAGUGAAA -20
Get sequence
Mature sequence

Pve-Mir-2-o76-v2_3p

mirBase accessionNone
Sequence
38- UCACAGCCAGCUUUGAUGAGC -59
Get sequence