MirGeneDB 2.1

MirGeneDB ID

Sme-Mir-2-o56

Family name MIR-2 (all species)
Seed AUCACAG
Species Freshwater planarian (Schmidtea mediterranea)
MiRBase ID sme-mir-2f
Paralogues Sme-Mir-2-o51a  Sme-Mir-2-o51b  Sme-Mir-2-o52  Sme-Mir-2-o53  Sme-Mir-2-o54  Sme-Mir-2-o55  Sme-Mir-2-o57  Sme-Mir-2-o58 
Orthologues
Node of Origin (locus) S. mediterranea
Node of Origin (family) Protostomia
Genome context
(Sme_GCA_002600895.1_ASM260089v1_alt)
NNSW01000025_dd_Smes_g4_25: 5887621-5887681 [+] UCSC Ensembl
Clustered miRNAs
(< 50kb from Mir-2-o56)
Mir-71-P19 NNSW01000025_dd_Smes_g4_25: 5887508-5887571 [+] UCSC Ensembl
Mir-2-o56 NNSW01000025_dd_Smes_g4_25: 5887621-5887681 [+] UCSC Ensembl
Mir-2-o57 NNSW01000025_dd_Smes_g4_25: 5887731-5887790 [+] UCSC Ensembl
Precursor
(pre-Mir +30nt flank)
CAAAUGUUUAAAUUACAAAUGAUAAAAGGCAAUCUGAAGCUGGAUGUGUUAUGAAGCUUUUUUAUCAUAUCACAGCCAUGCUACAGAGUUACCAAACGUUUGCAAACGUCUCUAUGAACGG
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Structure
        10        20         30         40         50         
CAAAUGUUUAAAUUACAAAUGAUAAAA-  CAA-    A   -|  A    U    AAGCU 
                            GG    UCUG AGC UGG UGUG UAUG     U
                            CC    AGAC UCG ACC ACAC AUAC     U
GGCAAGUAUCUCUGCAAACGUUUGCAAA  AUUG    A   U^  G    U    UAUUU 
 .       110       100        90        80        70        60
Deep sequencing
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CommentIt is not clear either from phylogenetic or syntenic information how many Mir-2 genes were present in the last common ancestor of protostomes and how the multiple paralogues in lophotrochozoans relate to the four Mir-2 genes in arthropods. Thus all lophotrochozoan genes are classified as orphans pending further data and analysis.
3' NTU Unknown
MotifsCNNC at 3p(+17)
Tissue expression
 +
Se Se Se Se Se Se Se Se Se Se Se Se Ne Wh Wh Wh
Star sequence

Sme-Mir-2-o56_5p* (predicted)

mirBase accessionMIMAT0011410
Sequence
0- AAUCUGAAGCUGGAUGUGUUAUG -23
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Mature sequence

Sme-Mir-2-o56_3p

mirBase accessionMIMAT0011411
Sequence
37- UAUCACAGCCAUGCUACAGAGUUA -61
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