Mir-34-P3b

MirGeneDB ID

Mmu-Mir-34-P3b

Family name

MIR-34 (all species)

Seed

GGCAGUG

Species

House mouse (Mus musculus)

MiRBase ID

mmu-mir-449b

Paralogues

Mmu-Mir-34-P1 Mmu-Mir-34-P2a Mmu-Mir-34-P2b Mmu-Mir-34-P3a Mmu-Mir-34-P3c

Orthologues

Aae-Mir-34 Ami-Mir-34-P3b Asu-Mir-34 Bge-Mir-34 Bta-Mir-34-P3b Cbr-Mir-34 Cel-Mir-34 Cfa-Mir-34-P3b Cgi-Mir-34 Cin-Mir-34 Cli-Mir-34-P3b Cmi-Mir-34-P3b Cpi-Mir-34-P3b Cte-Mir-34 Dan-Mir-34 Dma-Mir-34 Dme-Mir-34 Dmo-Mir-34 Dpu-Mir-34 Dsi-Mir-34 Dya-Mir-34 Efe-Mir-34 Esc-Mir-34 Ete-Mir-34-P3b Gga-Mir-34-P3b Gja-Mir-34-P3b Hsa-Mir-34-P3b Isc-Mir-34 Lch-Mir-34-P3b Lgi-Mir-34 Loc-Mir-34-P3b Mdo-Mir-34-P3b Mml-Mir-34-P3b Npo-Mir-34 Oan-Mir-34-P3b Obi-Mir-34 Ocu-Mir-34-P3b Ovu-Mir-34 Pbv-Mir-34-P3b Pfl-Mir-34 Pma-Mir-34-P3 Pmi-Mir-34 Rno-Mir-34-P3b Sha-Mir-34-P3b Sko-Mir-34 Spt-Mir-34-P3b Spu-Mir-34 Sto-Mir-34-P3b Tca-Mir-34 Xbo-Mir-34 Xla-Mir-34-P3b1 Xla-Mir-34-P3b2 Xtr-Mir-34-P3b

Node of Origin (locus)

Gnathostomata

Node of Origin (family)

Bilateria

Genome context
(mm10)

chr13: 113037429-113037487 [+] UCSC Ensembl

Clustered miRNAs
(< 50kb from Mir-34-P3b)

Mir-34-P3a chr13: 113036008-113036070 [+] UCSC Ensembl
Mir-34-P3b chr13: 113037429-113037487 [+] UCSC Ensembl
Mir-34-P3c chr13: 113037549-113037610 [+] UCSC Ensembl

Precursor
(pre-Mir +30nt flank)

UGUGAAAAUCCGAACUUGCCAGACUCGGGUAGGCAGUGUUGUUAGCUGGCUGCGUUGGGUCAGGCCAGCAGCCACAGCUACCCUGCCACUUCCUUCUGGCUGGGUUCUUCUUGUUAAUG

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Structure

        10          20        30        40        50        60
UGUGAAAAUCCGAACUU--|     CUC    A     U  U   AGC       GUUGGG 
                   GCCAGA   GGGU GGCAG GU GUU   UGGCUGC      U
                   CGGUCU   UUCA CCGUC CA CGA   ACCGACG      C
GUAAUUGUUCUUCUUGGGU^     UCC    -     C  U   C--       ACCGGA 
       110       100        90         80          70

Deep sequencing

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Comment

This is a Group 2 in human according to Kim et al but because there is a templated 3' U it is not possible according to read data to classify it as such in other taxa although the secondary structure is consistent with this categorization.

3' NTU

Yes

Motifs

UG at 5p(-14), CNNC at 3p(+17)

Tissue expression

Bo	Br	Br	Ce	Em	Em	He	In	Ki	Li	Lu	Mu	Ov	Pa	Sk	Sp	Sp	Te

Mature sequence

Mmu-Mir-34-P3b_5p

mirBase accession

MIMAT0005447

Sequence

0- AGGCAGUGUUGUUAGCUGGCUGCG -24

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Proposed targets

microrna.org: MIMAT0005447
TargetScanVert: mmu-miR-449b
miRDB: MIMAT0005447

Star sequence

Mmu-Mir-34-P3b_3p*

mirBase accession

None

Sequence

38- CAGCCACAGCUACCCUGCCAC -59

Get sequence