MirGeneDB 2.1

MirGeneDB ID

Mdo-Mir-34-P3b

Family name MIR-34 (all species)
Seed GGCAGUG
Species Gray short-tailed opossum (Monodelphis domestica)
MiRBase ID mdo-mir-449b
Paralogues Mdo-Mir-34-P1  Mdo-Mir-34-P2a  Mdo-Mir-34-P2b  Mdo-Mir-34-P3c  Mdo-Mir-34-P3d 
Orthologues Aae-Mir-34  Ami-Mir-34-P3b  Asu-Mir-34  Bge-Mir-34  Bta-Mir-34-P3b  Cbr-Mir-34  Cel-Mir-34  Cfa-Mir-34-P3b  Cgi-Mir-34  Cin-Mir-34  Cli-Mir-34-P3b  Cmi-Mir-34-P3b  Cpi-Mir-34-P3b  Cte-Mir-34  Dan-Mir-34  Dma-Mir-34  Dme-Mir-34  Dmo-Mir-34  Dpu-Mir-34  Dsi-Mir-34  Dya-Mir-34  Efe-Mir-34  Esc-Mir-34  Ete-Mir-34-P3b  Gga-Mir-34-P3b  Gja-Mir-34-P3b  Hsa-Mir-34-P3b  Isc-Mir-34  Lch-Mir-34-P3b  Lgi-Mir-34  Loc-Mir-34-P3b  Mml-Mir-34-P3b  Mmu-Mir-34-P3b  Npo-Mir-34  Oan-Mir-34-P3b  Obi-Mir-34  Ocu-Mir-34-P3b  Ovu-Mir-34  Pbv-Mir-34-P3b  Pfl-Mir-34  Pma-Mir-34-P3  Pmi-Mir-34  Rno-Mir-34-P3b  Sha-Mir-34-P3b  Sko-Mir-34  Spt-Mir-34-P3b  Spu-Mir-34  Sto-Mir-34-P3b  Tca-Mir-34  Xbo-Mir-34  Xla-Mir-34-P3b1  Xla-Mir-34-P3b2  Xtr-Mir-34-P3b 
Node of Origin (locus) Gnathostomata
Node of Origin (family) Bilateria
Genome context
(monDom5_add)
3: 17545756-17545815 [-] UCSC Ensembl
Clustered miRNAs
(< 50kb from Mir-34-P3b)
Mir-34-P3d 3: 17544591-17544650 [-] UCSC Ensembl
Mir-34-P3c 3: 17545614-17545674 [-] UCSC Ensembl
Mir-34-P3b 3: 17545756-17545815 [-] UCSC Ensembl
Precursor
(pre-Mir +30nt flank)
AGAAUACCGUUGCCAUUGCCAGGGUCAGGUAGGCAGUGCGCUGUAAGCUGGCUGCUUGGCUCAAUUUAGCAGUCAGGACUGCCCUGCCACUUGCUCCUGGACUCGUUCAUCUUCUUUAAC
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Structure
        10          20        30        40           50        
AGAAUACCGUUGCCAUUG--     GU     A     U   ---|  UAA    GCUGCUU 
                    CCAGG  CAGGU GGCAG GCG   CUG   GCUG       G
                    GGUCC  GUUCA CCGUC CGU   GAC   CGAU       G
CAAUUUCUUCUACUUGCUCA     UC     -     C   CAG^  UGA    UUAACUC 
.       110       100        90         80        70        60
Deep sequencing
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CommentThis is a Group 2 in human according to Kim et al but because there is a templated 3' U it is not possible according to read data to classify it as such in other taxa although the secondary structure is consistent with this categorization.
3' NTU Yes
MotifsUG at 5p(-14), CNNC at 3p(+17)
Tissue expression
 +
Br Ce He Ki Te
Mature sequence

Mdo-Mir-34-P3b_5p

mirBase accessionMIMAT0028582
Sequence
0- AGGCAGUGCGCUGUAAGCUGG -21
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Proposed targets TargetScanVert: mdo-miR-449b-5p
Co-mature sequence

Mdo-Mir-34-P3b_3p

mirBase accessionMIMAT0028583
Sequence
39- CAGUCAGGACUGCCCUGCCAC -60
Get sequence
Proposed targets TargetScanVert: mdo-miR-449b-3p