MirGeneDB 2.1

MirGeneDB ID

Hsa-Mir-10-P2c

Family name MIR-10 (all species)
Seed ACCCGUA
Species Human (Homo sapiens)
MiRBase ID hsa-mir-99a
Paralogues Hsa-Mir-10-P1b-v1  Hsa-Mir-10-P1b-v2  Hsa-Mir-10-P1c-v1  Hsa-Mir-10-P1c-v2  Hsa-Mir-10-P2b  Hsa-Mir-10-P2d  Hsa-Mir-10-P3b  Hsa-Mir-10-P3c  Hsa-Mir-10-P3d 
Orthologues Aae-Mir-10-P2  Aca-Mir-10-P2c  Ami-Mir-10-P2c  Bfl-Mir-10-P2-v1  Bfl-Mir-10-P2-v2  Bge-Mir-10-P2  Bla-Mir-10-P2-v1  Bla-Mir-10-P2-v2  Bpl-Mir-10-P2  Bta-Mir-10-P2c  Cbr-Mir-10-P2  Cel-Mir-10-P2  Cfa-Mir-10-P2c  Cgi-Mir-10-P2  Cin-Mir-10-P2  Cli-Mir-10-P2c  Cmi-Mir-10-P2c  Cpi-Mir-10-P2c  Cpo-Mir-10-P2c  Cte-Mir-10-P2  Dan-Mir-10-P2  Dma-Mir-10-P2  Dme-Mir-10-P2  Dmo-Mir-10-P2  Dno-Mir-10-P2c  Dpu-Mir-10-P2  Dre-Mir-10-P2c1  Dre-Mir-10-P2c2  Dsi-Mir-10-P2  Dya-Mir-10-P2  Ete-Mir-10-P2c  Gga-Mir-10-P2c  Gja-Mir-10-P2c  Gmo-Mir-10-P2c2  Isc-Mir-10-P2  Lan-Mir-10-P2  Lch-Mir-10-P2c  Lgi-Mir-10-P2  Loc-Mir-10-P2c  Mal-Mir-10-P2c2  Mml-Mir-10-P2c  Mmu-Mir-10-P2c  Mun-Mir-10-P2c  Npo-Mir-10-P2  Nve-Mir-10  Oan-Mir-10-P2c  Obi-Mir-10-P2  Ocu-Mir-10-P2c  Ovu-Mir-10-P2  Pbv-Mir-10-P2c  Pfl-Mir-10-P2  Pmi-Mir-10-P2  Rno-Mir-10-P2c  Sha-Mir-10-P2c  Sko-Mir-10-P2  Spt-Mir-10-P2c  Sto-Mir-10-P2c  Tca-Mir-10-P2  Tgu-Mir-10-P2c  Xbo-Mir-10-P2  Xbo-Mir-10-P2-as  Xla-Mir-10-P2c3  Xla-Mir-10-P2c4  Xtr-Mir-10-P2c 
Node of Origin (locus) Gnathostomata
Node of Origin (family) Eumetazoa
Genome context
(hg38)
chr21: 16539101-16539159 [+] UCSC Ensembl
Clustered miRNAs
(< 50kb from Mir-10-P2c)
Mir-10-P2c chr21: 16539101-16539159 [+] UCSC Ensembl
Let-7-P1c chr21: 16539838-16539904 [+] UCSC Ensembl
Precursor
(pre-Mir +30nt flank)
GGCCCAUGCAAGAUGUUGCCCAUUGGCAUAAACCCGUAGAUCCGAUCUUGUGGUGAAGUGGACCGCACAAGCUCGCUUCUAUGGGUCUGUGUCAGUGUGGUAAUCUGACAAAAUGCUAU
Get precursor sequence
Structure
        10         20         30        40        50         
GGCCCAUGCAAGAUGUU-   -|         A         UC   U      GUGAAG 
                  GCC CAUUGGCAUA ACCCGUAGA  CGA CUUGUG      \
                  UGG GUGACUGUGU UGGGUAUCU  GCU GAACAC      U
UAUCGUAAAACAGUCUAA   U^         C         UC   C      GCCAGG 
       110       100        90        80        70        60
Deep sequencing
Go to detailed chart
CommentBased on the 3' moR reads in human (P2b) and platypus (P2c) it appears that this is a Group 2 miRNA.
3' NTU Yes
MotifsUG at 5p(-14), UGUG in loop
Tissue expression
 +
Ad Ar Bl Bo Bo Bo Bo Bo Br Br Br Br Br Br Br Br Br Br Br Es Ga He He He He He Ki Li Lu Ly Mu Ne Pa Pl Pl Sk Sp Sp St Su Te Th To Tr Ve
Mature sequence

Hsa-Mir-10-P2c_5p

mirBase accessionMIMAT0000097
Sequence
0- AACCCGUAGAUCCGAUCUUGUG -22
Get sequence
Proposed targets microrna.org: MIMAT0000097
TargetScanVert: hsa-miR-99a-5p
TargetMiner: hsa-miR-99a-5p
miRDB: MIMAT0000097
Star sequence

Hsa-Mir-10-P2c_3p*

mirBase accessionMIMAT0004511
Sequence
37- CAAGCUCGCUUCUAUGGGUCUG -59
Get sequence
Proposed targets microrna.org: MIMAT0004511
TargetScanVert: hsa-miR-99a-3p
TargetMiner: hsa-miR-99a-3p
miRDB: MIMAT0004511